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N-2-(7-methoxy-1-naphthyl)ethylacetamide, a Potent Melatonin Analog

机译:N- 2-(7-甲氧基-1-萘基)乙基乙酰胺,有效的褪黑激素类似物

摘要

The four crystallographically independent molecules present in the unit cell of N-[2-(7-methoxy-1-naphthyl)ethyl]acetamide, C15H17NO2, are very similar; the naphthalene ring is planar, the methoxy substituent is staggered and the side chain is oriented so that the amide and aromatic groups are approximately parallel. This conformation of the longer side chain is different from the fully extended conformation observed in the neurohormone melatonin.
机译:N- [2-(7-甲氧基-1-萘基)乙基]乙酰胺C15H17NO2的晶胞中存在的四个晶体学独立分子非常相似;萘环是平面的,甲氧基取代基是交错的,侧链是定向的,因此酰胺和芳族基团近似平行。较长侧链的这种构象不同于在神经激素褪黑激素中观察到的完全延伸的构象。

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