The long term objective of this research is to develop a collapsible, percutaneously inserted, axial flow blood pump to improve blood flow in the cavopulmonary circulation. Through this research, the experimental evaluation of five blood pump prototypes and hemolysis testing of one blood pump prototype were performed. All prototypes demonstrated acceptable hydraulic performance. A comparison of the experimental results with numerical predictions demonstrated a 10-20% deviation, an acceptable range per industry standard. Hemolysis testing of a four bladed adult blood pump showed plasma free hemoglobin level of 20.04 mg/dL and maximum NIH (normalized index of hemolysis) level was 0.017 g/100L. This thesis project serves as a solid foundation from which to continue development of this suited intravascular axial flow blood pump. Successful completion of this research will lead to a novel percutaneously inserted axial flow pump for infants and adult patients with a failing Fontan physiology.
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机译：这项研究的长期目标是开发一种可折叠，经皮插入的轴流血泵，以改善腔肺循环中的血流。通过这项研究，对五个血泵原型进行了实验评估，并对一个血泵原型进行了溶血测试。所有原型均显示出可接受的液压性能。实验结果与数值预测的比较表明，偏差为10-20％，根据行业标准是可以接受的范围。四叶成人血泵的溶血测试显示血浆游离血红蛋白水平为20.04 mg / dL，最大NIH（溶血标准化指数）水平为0.017 g / 100L。该论文项目为继续开发这种合适的血管内轴向流血泵奠定了坚实的基础。该研究的成功完成将导致一种新型的经皮插入式轴流泵，该泵适用于丰坦生理机能不佳的婴儿和成人患者。
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