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Design and Development of a High Performance Pinhole Array Dual Head SPECT Using Monte Carlo Simulation

机译:基于蒙特卡洛模拟的高性能针孔阵列双探头SPECT设计与开发

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摘要

The Purpose of this study is to investigate the performance of a dual head SPECT system having an array of pinholes as a collimator. Several analytical methods are used to evaluate the performance of the given pinhole array detector module design. Monte Carlo simulation studies using Geant4 Application for Tomographic Emission (GATE) validate the performance of this novel dual head SPECT where a cylindrical water phantom is imaged. We are proposing a pinhole array detector module with 48mm by 48mm of active area behind an array of 100 pinholes laid out in a 10 by 10 lattice. This configuration allows high detection efficiency and excellent sensitivity in SPECT imaging. The system is based on a pixelated array of NaI crystals (100 × 100 × 10mm elements) coupled with an array of position sensitive photomultiplier tubes (PSPMTs). The basic characteristics of this system were evaluated with pinhole apertures of 0.5mm, 1mm, 1.5mm, 2mm, 2.5mm and 3mm respectively. A conventional filtered back projection algorithm was used to reconstruct the images. Performance evaluation of this system indicates that high quality images can be obtained for in vivo imaging.
机译:本研究的目的是研究具有针孔阵列作为准直仪的双头SPECT系统的性能。几种分析方法用于评估给定针孔阵列检测器模块设计的性能。使用Geant4的X射线断层摄影应用(GATE)进行的蒙特卡洛模拟研究验证了这种新颖的双头SPECT的性能,在该双头SPECT上成像了圆柱形水模。我们提出了一种针孔阵列检测器模块,该模块的有效面积为48mm x 48mm,位于以10 x 10的格子形式排列的100个针孔阵列之后。这种配置在SPECT成像中具有很高的检测效率和出色的灵敏度。该系统基于NaI晶体的像素化阵列(100×100×10mm元素)以及位置敏感的光电倍增管(PSPMT)阵列。用分别为0.5mm,1mm,1.5mm,2mm,2.5mm和3mm的针孔评估了该系统的基本特性。使用常规的滤波反投影算法来重建图像。该系统的性能评估表明,可以为体内成像获得高质量的图像。

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