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Pharmacokinetics and pharmacodynamics of orally administered acetylenic tricyclic bis(cyanoenone), a highly potent Nrf2 activator with a reversible covalent mode of action

机译：口服乙炔三环双（氰基烯酮），一种具有可逆共价作用方式的高效Nrf2激活剂，其药代动力学和药效学

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Kostov Rumen V.; Knatko Elena V.; McLaughlin Lesley A.; Henderson Colin J.; Zheng Suqing; Huang Jeffrey T.-J.; Honda Tadashi; Dinkova-Kostova Albena T.;
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1. Pharmacokinetics and pharmacodynamics of orally administered acetylenic tricyclic bis(cyanoenone), a highly potent Nrf2 activator with a reversible covalent mode of action [J] . Kostov Rumen V., Knatko Elena V., McLaughlin Lesley A., Biochemical and Biophysical Research Communications . 2015,第3期

机译：口服乙炔三环双（氰基烯酮），一种高效的Nrf2激活剂，具有可逆的共价作用方式，其药代动力学和药效学
2. Safety, pharmacokinetics and pharmacodynamics of BI 705564, a highly selective, covalent inhibitor of Bruton's tyrosine kinase, in Phase I clinical trials in healthy volunteers [J] . Litzenburger Tobias, Steffgen Juergen, Benediktus Ewald, British Journal of Clinical Pharmacology . 2021,第4期

机译：BI 705564的安全性，药代动力学和药效学，BRUTON酪氨酸激酶的高度选择性，共价抑制剂，其在健康志愿者的临床试验中
3. Safety, pharmacokinetics and pharmacodynamics of BI 705564, a highly selective, covalent inhibitor of Bruton's tyrosine kinase, in Phase I clinical trials in healthy volunteers [J] . Tobias Litzenburger, Jürgen Steffgen, Ewald Benediktus, British journal of clinical pharmacology . 2021,第4期

机译：BI 705564的安全性，药代动力学和药效学，BRUTON酪氨酸激酶的高度选择性，共价抑制剂，其在健康志愿者的临床试验中
4. Physiologically-Based Pharmacokinetic and Pharmacodynamic Modeling of Unfractionated Heparin to Predict Activated Clotting Time [C] . Filippo Regorda, Emiliano Vigoni, Giuseppe Pesenti European Symposium on Computer Aided Chemical engineering . 2020

机译：未分割肝素的基于生理学药代动力学和药效学建模预测激活凝血时间
5. Mode of action studies with phthalate acid monoesters: Pharmacokinetic and pharmacodynamic factors affecting steroidogenesis. [D] . Clewell, Rebecca Ann. 2009

机译：邻苯二甲酸单酯的作用方式研究：影响类固醇生成的药代动力学和药效学因素。
6. Pharmacokinetics and pharmacodynamics of orally administered acetylenic tricyclic bis(cyanoenone) a highly potent Nrf2 activator with a reversible covalent mode of action [O] . Rumen V. Kostov, Elena V. Knatko, Lesley A. McLaughlin, -1

机译：口服乙炔三环双（氰基烯酮）一种高效的Nrf2激活剂具有可逆的共价作用方式其药代动力学和药效学
7. Pharmacokinetics and pharmacodynamics of orally administered acetylenic tricyclic bis(cyanoenone), a highly potent Nrf2 activator with a reversible covalent mode of action [O] . Kostov Rumen V., Knatko Elena V., McLaughlin Lesley A., 2015

机译：口服乙炔三环 bis （氰基烯酮），一种高效的Nrf2激活剂，具有可逆的共价作用方式，其药代动力学和药效学
8. A Physiologically-based Pharmacokinetic and Pharmacodynamic Model for the Oral Dosing of Rats with Ethyl Acrylate and Its Implications for Risk Assessment (paper Preprint) W-letter. [R] . 1992

机译：基于生理学的药代动力学和药效学模型，用于口服丙烯酸乙酯大鼠及其对风险评估的影响（纸质预印本）W字母。

Pharmacokinetics and pharmacodynamics of orally administered acetylenic tricyclic bis(cyanoenone), a highly potent Nrf2 activator with a reversible covalent mode of action

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