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Structure-based design and in-parallel synthesis of inhibitors of AmpC β-lactamase

机译：基于结构的设计和AmpCβ-内酰胺酶抑制剂的并行合成

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Tondi Donatella; Powers Rachel A; Caselli Emilia; Negri Marı́a-Cristina; Blázquez Jesús; Costi Maria Paola; Shoichet Brian K;
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年度 2001
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1. Design, synthesis and biological evaluation of non-covalent AmpC beta-lactamases inhibitors [J] . Genovese Filippo, Lazzari Sandra, Venturi Ettore, Medicinal chemistry research: an international journal for rapid communications on design and mechanisms of action of biologically active agents . 2017,第5期

机译：非共价AMPCβ-内酰胺酶抑制剂的设计，合成和生物学评价
2. X-ray crystallographic analysis of IMP-1 metallo-β-lactamase complexed with a 3-aminophthalic acid derivative, structure-based drug design, and synthesis of 3,6-disubstituted phthalic acid derivative inhibitors [J] . HiraiwaY., SaitoJ., WatanabeT., Bioorganic and Medicinal Chemistry Letters . 2014,第20期

机译：与3-氨基邻苯二甲酸衍生物复合的IMP-1金属β-内酰胺酶的X射线晶体学分析，基于结构的药物设计以及3,6-二取代邻苯二甲酸衍生物抑制剂的合成
3. 4-Substituted Trinems as Broad Spectrum beta-Lactamase Inhibitors:Structure-Based Design,Synthesis,and Biological Activity [J] . Ivan Plantan, Lovro Selic, Tomaz Mesar Journal of Medicinal Chemistry . 2007,第17期

机译：4-取代的三聚氰胺作为广谱β-内酰胺酶抑制剂：基于结构的设计，合成和生物活性
4. Structure-Based Design, Synthesis and Evaluation of Novel Peptidic Inhibitors of Thrombin-Induced Activation of Platelets Aggregation [C] . Janet Gonzalez, Anna Babinska, Ebenezer L.V. Ewu American Peptide Symposium . 2015

机译：基于结构的设计，合成和评价血小板诱导的血小板聚集活化的激活
5. Structure-Based Drug Design in Medicinal Chemistry: I. Development of Translesion Synthesis Inhibitors II. Synthesis and Biological Evaluation of Sulfonyl Piperazine Derivatives for LpxH Inhibition [D] . Lee, Minhee 2017

机译：药物化学中基于结构的药物设计：I.跨病变合成抑制剂的开发II。磺酰哌嗪衍生物对LpxH的抑制作用及其合成及生物学评价
6. Structure-based Design of Potent HIV-1 Protease Inhibitors with Modified P1 - Biphenyl Ligands: Synthesis Biological Evaluation and Enzyme-inhibitor X-ray Structural studies [O] . Arun K. Ghosh, Xufen Yu, Heather L. Osswald, -1

机译：具有修饰的P1-联苯配体的有效HIV-1蛋白酶抑制剂的结构设计：合成生物学评估和酶抑制剂X射线结构研究
7. 4-Substituted Trinems as Broad Spectrum b-Lactamase Inhibitors: Structure-Based Design, Synthesis, and Biological Activity [O] . -1

机译：4-取代的Trinems作为广谱B-内酰胺酶抑制剂：基于结构的设计，合成和生物活性

Structure-based design and in-parallel synthesis of inhibitors of AmpC β-lactamase

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