首页> 外文OA文献 >METHADONE-INDUCED QTC PROLONGATION IS ASSOCIATED WITH CYP2C19 GENOTYPE AND WITH PLASMA ETHYLIDENE-1,5-DIMETHYL-3,3-DIPHENYLPYRROLIDENE (EDDP) CONCENTRATION: A POSSIBLE MECHANISTIC LINK

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METHADONE-INDUCED QTC PROLONGATION IS ASSOCIATED WITH CYP2C19 GENOTYPE AND WITH PLASMA ETHYLIDENE-1,5-DIMETHYL-3,3-DIPHENYLPYRROLIDENE (EDDP) CONCENTRATION: A POSSIBLE MECHANISTIC LINK

机译：美沙酮诱导的QTC延长与CYP2C19基因型和血浆中亚乙基-1,5-二甲基-3,3-二苯基吡咯烷酮（EDDP）浓度有关：可能的机理联系

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Carlquist John; Moody David; Johnson Eric; Jacobsen Marian; Huntinghouse John; Rollo Jeffrey; Knight Stacey; Fang Wenfang B.; Niemann Dawn; Morgan Mark; Muhlestein J.; Anderson Jeffrey;
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1. A Possible Mechanistic Link Between the CYP2C19 Genotype, the Methadone Metabolite Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidene (EDDP), and Methadone-Induced Corrected QT Interval Prolongation in a Pilot Study [J] . Carlquist John F., Moody David E., Knight Stacey, Molecular diagnosis & therapy . 2015,第2期

机译：CYP2C19基因型，美沙酮代谢物亚乙基-1,5-二甲基-3,3-二苯基吡咯烷（EDDP）和美沙酮诱导的校正QT间隔延长之间的可能机理联系
2. Relationship Between the CYP2C19 Phenotype Using the Voriconazole-to-Voriconazole N-Oxide Plasma Concentration Ratio and Demographic and Clinical Characteristics of Japanese Patients With Different CYP2C19 Genotypes [J] . Niioka Takenori, Fujishima Naohito, Abumiya Maiko, Therapeutic Drug Monitoring . 2017,第5期

机译：不同CYP2C19基因型的voriconazole-voriconazole n氧化术血浆浓度比和日本患者人口统计学和临床特征的CYP2C19表型的关系
3. Case files of the Drexel University medical toxicology fellowship: Methadone-induced QTc prolongation [J] . Stella C. Wong, James R. Roberts Journal of Medical Toxicology . 2007,第4期

机译：Drexel大学医学毒理学研究金的案例文件：美沙酮诱导的QTc延长
4. Major influence of CYP2C19 genotype on the steady-state concentration of N~desmethylclobazam [C] . T. Takahashi Korean Child Neurology Society Congress . 2009

机译：CYP2C19基因型对N〜Desmethylbobazam稳态浓度的主要影响
5. Evaluation of Methadone-Induced QTc Prolongation in a Veteran Population [O] . Chelsie B. Heesch, Amy E. Copfer, Stephanie J. Davis, 2015

机译：美沙酮诱导的退伍军人中QTc延长的评估
6. QTC PROLONGATION CORRELATES WITH PLASMA ETHYLIDENE-1.5-DIMETHYL-3.3-DIPHENYLPYRROLIDENE (EDDP) AMONG SUBJECTS INITIATING METHADONE MAINTENANCE THERAPY [O] . Carlquist John, Moody David, Johnson Eric, 2013

机译：在开始美沙酮维持治疗的受试者中，QTC延长与血浆中的乙烯-1.5-二甲基-3.3-二苯基吡咯烷酮（EDDP）相关

METHADONE-INDUCED QTC PROLONGATION IS ASSOCIATED WITH CYP2C19 GENOTYPE AND WITH PLASMA ETHYLIDENE-1,5-DIMETHYL-3,3-DIPHENYLPYRROLIDENE (EDDP) CONCENTRATION: A POSSIBLE MECHANISTIC LINK

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