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The anti-fibrotic effects of CCN1/CYR61 in primary portal myofibroblasts are mediated through induction of reactive oxygen species resulting in cellular senescence, apoptosis and attenuated TGF-β signaling

机译：CCN1 / CYR61在原发性门脉成纤维细胞中的抗纤维化作用是通过诱导活性氧导致细胞衰老，凋亡和TGF-β信号转导减弱而介导的

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Borkham-Kamphorst Erawan; Schaffrath Christian; Van de Leur Eddy; Haas Ute; Tihaa Lidia; Meurer Steffen K.; Nevzorova Yulia A.; Liedtke Christian; Weiskirchen Ralf;
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1. The anti-fibrotic effects of CCN1/CYR61 in primary portal myofibroblasts are mediated through induction of reactive oxygen species resulting in cellular senescence, apoptosis and attenuated TGF-β signaling [J] . Borkham-KamphorstE., SchaffrathC., VandeLeurE., Biochimica et biophysica acta. Molecular cell research . 2014,第5期

机译：CCN1 / CYR61在原发性门脉成纤维细胞中的抗纤维化作用是通过诱导活性氧导致细胞衰老，凋亡和减弱的TGF-β信号传导而介导的
2. Matricellular Protein CCN1 Promotes Regression of Liver Fibrosis through Induction of Cellular Senescence in Hepatic Myofibroblasts [J] . Ki-Hyun Kim, Chih-Chiun Chen, Ricardo I. Monzon, Molecular and Cellular Biology . 2013,第10期

机译：基质细胞蛋白CCN1通过诱导肝成纤维细胞中细胞衰老促进肝纤维化的退化。
3. Induction of apoptosis by casticin in cervical cancer cells through reactive oxygen species-mediated mitochondrial signaling pathways. [J] . Chen D, Cao J, Tian L, Oncology reports . 2011,第5期

机译：蓖麻毒素通过活性氧介导的线粒体信号传导途径诱导宫颈癌细胞凋亡。
4. Ugonin K induces Cell Cycle Arrest and Apoptosis through Reactive oxygen species/Apoptosis Signal Pathway in Human Skin Cancer Cells [C] . Leong-Perng Chan, Tzung-Han Chou, Guey-Horng Wang, International Conference on Manufacturing Science and Engineering . 2013

机译：Ugonin K通过在人体皮肤癌细胞中的活性氧物质/凋亡信号途径诱导细胞周期停滞和细胞凋亡
5. GMZ27 is a new organic arsenic derivative with anti-leukemic activity, via the induction of reactive oxygen species through NADPH oxidase and mitochondrial pathway that lead to leukemia cell apoptosis. [D] . Cheng, Xiaodong. 2006

机译：GMZ27是一种具有抗白血病活性的新型有机砷衍生物，通过NADPH氧化酶和线粒体途径诱导活性氧，导致白血病细胞凋亡。
6. TNFα-Induced Apoptosis Enabled by CCN1/CYR61: Pathways of Reactive Oxygen Species Generation and Cytochrome c Release [O] . Vladislava Juric, Chih-Chiun Chen, Lester F. Lau -1

机译：TNFα诱导的细胞凋亡通过启用CCN1 / CYR61：活性氧的产生和细胞色素c释放的途径
7. The anti-fibrotic effects of CCN1/CYR61 in primary portal myofibroblasts are mediated through induction of reactive oxygen species resulting in cellular senescence, apoptosis and attenuated TGF-β signaling [O] . Borkham-Kamphorst, Erawan, Schaffrath, Christian, van de Leur, Eddy, 2014

机译：CCN1 / CYR61在原发性门脉成纤维细胞中的抗纤维化作用是通过诱导活性氧而介导的，从而导致细胞衰老，凋亡和TGF-β信号减弱

The anti-fibrotic effects of CCN1/CYR61 in primary portal myofibroblasts are mediated through induction of reactive oxygen species resulting in cellular senescence, apoptosis and attenuated TGF-β signaling

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