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Hypoxia-induced activation of HIF-1: role of HIF-1α-Hsp90 interaction

机译：低氧诱导的HIF-1激活：HIF-1α-Hsp90相互作用的作用

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Minet E; Mottet D; Michel G; Roland I; Raes M; Remacle J; Michiels C;
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年度 1999
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1. RACK1 competes with HSP90 for binding to HIF-1 alpha and is required for O-2-independent and HSP90 inhibitor-induced degradation of HIF-1 alpha [J] . Liu YV, Baek JH, Zhang H, Molecular cell . 2007,第26期

机译：RACK1与HSP90竞争与HIF-1 alpha的结合，并且是O-2独立和HSP90抑制剂诱导的HIF-1 alpha降解所必需的
2. SENP1 promotes hypoxia-induced cancer stemness by HIF-1 alpha deSUMOylation and SENP1/HIF-1 alpha positive feedback loop [J] . Cui Chun-Ping, Wong Carmen Chak-Lui, Kai Alan Ka-Lun, Gut: Journal of the British Society of Gastroenterology . 2017,第12期

机译：SeNP1通过HIF-1αdesumoylation和SenP1 / HIF-1α阳性反馈回路促进缺氧诱导的癌症茎
3. RACK1 mediates the advanced glycation end product-induced degradation of HIF-1 alpha in nucleus pulposus cells via competing with HSP90 for HIF-1 alpha binding [J] . Xu Yi-Chang, Gu Yong, Yang Jia-Ying, Cell biology international. . 2021,第6期

机译：Rack1通过与HIF-1α结合的Hsp90竞争，介导高级糖糖末端产物诱导的HIF-1α的HIF-1α降解
4. Pravastatin Attenuates Ceramide-Induced Cytotoxicity in Mouse Cerebral Endothelial Cells with HIF-1 Activation and VEGF Upregulation [C] . SHANG-DER CHEN, CHAUR-JONG HU, DING-I YANG, Asian Society for Mitochondrial Research and Medicine . 2005

机译：普伐他汀在小鼠脑内皮细胞中衰减宫胺诱导的细胞毒性，HIF-1活化和VEGF上调
5. AMPK-HDAC5 Pathway Facilitates Nuclear Accumulation of HIF-1α and Functional Activation of HIF-1 by Deacetylating Hsp70 in the Cytosol [D] . Chen, Shuyang 2015

机译：AMPK-HDAC5通路通过使细胞质中的Hsp70脱乙酰化来促进HIF-1α的核积累和HIF-1的功能激活。
6. RACK1 Competes with HSP90 for Binding to HIF-1α and is Required for O2-independent and HSP90 Inhibitor-induced Degradation of HIF-1α [O] . Ye V. Liu, Jin H. Baek, Huafeng Zhang, -1

机译：RACK1与HSP90竞争与HIF-1α的结合并且是O2依赖性和HSP90抑制剂诱导的HIF-1α降解所必需的
7. RACK1 Competes with HSP90 for Binding to HIF-1α and Is Required for O2-Independent and HSP90 Inhibitor-Induced Degradation of HIF-1α [O] . Ye V. Liu, Jin H. Baek, Huafeng Zhang, 2007

机译：Rack1与HSP90竞争，用于结合HIF-1α，HIF-1α的O2无关和HSP90抑制剂诱导的降解所需的HIF-1α

Hypoxia-induced activation of HIF-1: role of HIF-1α-Hsp90 interaction

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