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Mitochondrial DNA repair enzyme OGG1 is essential for protection against the downregulation of chondrocyte activity in OA

机译：线粒体DNA修复酶OGG1对于防止OA中软骨细胞活性的下调至关重要

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Yudoh K.; Karasawa R.; Yui N.;
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1. AMP-ACITVATED PROTEIN KINASE (AMPK) LIMITS MITOCHONDRIAL DNA DAMAGE IN HUMAN KNEE OA CHONDROCYTES BY UPREGULATION OF SIRT3 AND THE DNA REPAIR ENZYME OGG1 [J] . Liu-Bryan R., Wang Y., Terkeltaub R. Osteoarthritis and cartilage . 2015,第Suppla2期

机译：AMP激活的蛋白激酶（AMPK）通过上调SIRT3和DNA修复酶OGG1限制人膝软骨细胞的线粒体DNA损伤
2. AMP-ACITVATED PROTEIN KINASE (AMPK) LIMITS MITOCHONDRIAL DNA DAMAGE IN HUMAN KNEE OA CHONDROCYTES BY UPREGULATION OF SIRT3 AND THE DNA REPAIR ENZYME OGG1 [J] . Liu-Bryan R., Wang Y., Terkeltaub R. Osteoarthritis and cartilage . 2015,第Suppla2期

机译：AMP-Acitvated蛋白激酶（AMPK）通过Upregulation和DNA修复酶OGG1限制人膝部OA软骨细胞的线粒体DNA损伤。
3. The C-terminal αO helix of human Ogg1 is essential for 8-oxoguanine DNA glycosylase activity: the mitochondrial β-Ogg1 lacks this domain and does not have glycosylase activity [J] . J. A. Stuart, K. Hashiguchi, N. C. de Souza-Pinto, Nucleic acids research . 2004,第18期

机译：人类Ogg1的C端αO螺旋对于8-氧鸟嘌呤DNA糖基化酶的活性至关重要：线粒体β-Ogg1缺少该结构域，并且不具有糖基化酶活性
4. Changes in the repair of mitochondrial DNA during ageing due to exercise and caloric restriction [C] . Zeng Zhengzhong, Wen Li, Wu Zhiyi Internaional convention on science, education and medicine in sport;2008 ICSEMIS . 2008

机译：运动和热量限制导致衰老过程中线粒体DNA修复的变化
5. I. Synthesis of a cell-permeable heterodimeric library. II. Structural studies of the DNA-repair enzymes MutM and Ogg1 [D] . Finkelstein, Joshua Michael 2004

机译：I.细胞可渗透的异二聚体文库的合成。二。 DNA修复酶MutM和Ogg1的结构研究
6. The C-terminal αO helix of human Ogg1 is essential for 8-oxoguanine DNA glycosylase activity: the mitochondrial β-Ogg1 lacks this domain and does not have glycosylase activity [O] . K. Hashiguchi, J. A. Stuart, N. C. de Souza-Pinto, 2004

机译：人类Ogg1的C末端αO螺旋对于8-氧代鸟嘌呤DNA糖基化酶活性必不可少：线粒体β-Ogg1缺少此结构域且不具有糖基化酶活性
7. AMP-activated protein kinase (AMPK) limits mitochondrial DNA damage in human knee OA chondrocytes by upregulation of SIRT3 and the DNA repair enzyme OGG1 [O] . Liu-Bryan R., Wang Y., Terkeltaub R. 2015

机译：AMP激活的蛋白激酶（AMPK）通过上调SIRT3和DNA修复酶OGG1限制人膝OA软骨细胞的线粒体DNA损伤
8. Altering Cell Survival by Modulating Levels of Mitochondrial DNA Repair Enzymes [R] . Shokolenko, I. N. 2002

机译：通过调节线粒体DNa修复酶水平改变细胞存活

Mitochondrial DNA repair enzyme OGG1 is essential for protection against the downregulation of chondrocyte activity in OA

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