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Random Point Mutations with Major Effects on Protein-Coding Genes Are the Driving Force behind Premature Aging in mtDNA Mutator Mice

机译：对蛋白质编码基因有重大影响的随机点突变是mtDNA突变小鼠过早衰老的驱动力

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Edgar Daniel; Shabalina Irina; Camara Yolanda; Wredenberg Anna; Calvaruso Maria Antonietta; Nijtmans Leo; Nedergaard Jan; Cannon Barbara; Larsson Nils-Göran; Trifunovic Aleksandra;
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1. Random point mutations with major effects on protein-coding genes are the driving force behind premature aging in mtDNA mutator mice. [J] . Edgar D, Shabalina I, Camara Y Cell metabolism . 2009,第2期

机译：对蛋白质编码基因有重大影响的随机点突变是mtDNA突变小鼠过早衰老的驱动力。
2. Does premature aging of the mtDNA mutator mouse prove that mtDNA mutations are involved in natural aging? [J] . Khrapko K, Kraytsberg Y, de Grey AD, Aging cell. . 2006,第3期

机译：mtDNA mutator小鼠过早衰老是否证明mtDNA突变与自然衰老有关？
3. Does premature aging of the mtDNA mutator mouse prove that mtDNA mutations are involved in natural aging? [J] . Konstantin Khrapko, Yevgenya Kraytsberg, Aubrey DNJ de Grey, Aging cell. . 2006,第3期

机译：mtDNA mutator小鼠的过早衰老是否证明mtDNA突变与自然衰老有关？
4. Image Based Measurements of Single Cell mtDNA Mutation Load [C] . Amin Allalou, Frans M. van de Rijke, Roos Jahangir Tafrechi, Scandinavian Conference on Image Analysis(SCIA 2007); 20070610-14; Aalborg(DK) . 2007

机译：基于图像的单细胞mtDNA突变负荷测量
5. Biochemical and genetic characterization of mitochondrial encephalomyopathies resulting from mitochondrial-DNA (mtDNA) and nuclear DNA (nDNA) mutations. [D] . Zheng, Xianxian. 1990

机译：由线粒体DNA（mtDNA）和核DNA（nDNA）突变引起的线粒体脑肌病的生化和遗传特征。
6. The role of mtDNA mutations in the pathogenesis of age-related hearing loss in mice carrying a mutator DNA polymerase γ [O] . Shinichi Someya, Tatsuya Yamasoba, Gregory C. Kujoth, -1

机译：mtDNA突变在携带突变型DNA聚合酶γ的小鼠中与年龄相关的听力损失的发病机理中的作用
7. The role of mtDNA mutations in the pathogenesis of age-related hearing loss in mice carrying a mutator DNA polymerase γ [O] . Shinichi Someya, Tatsuya Yamasoba, Gregory C. Kujoth, 2008

机译：MTDNA突变在携带致脉状物DNA聚合酶γ的小鼠中与年龄相关的听力损失发病机制中的作用

Random Point Mutations with Major Effects on Protein-Coding Genes Are the Driving Force behind Premature Aging in mtDNA Mutator Mice

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