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The S100A9 inhibitor paquinimod (ABR-215757) reduces synovial activation, osteophyte formation and cartilage damage in experimental osteoarthritis

机译：S100A9抑制剂paquinimod（ABR-215757）可减少实验性骨关节炎中的滑膜活化，骨赘形成和软骨损伤

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Schelbergen R.F.; Blom A.B.; Leanderson T.; Eriksson H.; van den Berg W.B.; van der Kraan P.M.; van Lent P.L.;
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1. Prophylactic treatment with S100A9 inhibitor paquinimod reduces pathology in experimental collagenase-induced osteoarthritis [J] . R F Schelbergen, E J Geven, M H J van den Bosch, Annals of the Rheumatic Diseases: A Journal of Clinical Rheumatology and Connective Tissue Research . 2015,第12期

机译：具有S100A9抑制剂Paquinimod的预防性处理降低了实验性胶原酶诱导的骨关节炎的病理学
2. Alarmins S100A8/S100A9 aggravate osteophyte formation in experimental osteoarthritis and predict osteophyte progression in early human symptomatic osteoarthritis [J] . Schelbergen R. F. P., de Munter W., van den Bosch M. H. J., Annals of the Rheumatic Diseases: A Journal of Clinical Rheumatology and Connective Tissue Research . 2016,第1期

机译：Alarmins S100A8 / S100A9会加剧实验性骨关节炎中的骨赘形成并预测人类早期症状性骨关节炎中的骨赘进展
3. Synovial lining macrophages mediate osteophyte formation during experimental osteoarthritis. [J] . Blom AB, van Lent PL, Holthuysen AE, Osteoarthritis and cartilage . 2004,第8期

机译：滑膜衬里巨噬细胞在实验性骨关节炎期间介导骨赘形成。
4. Intra-Articular TSG-6 Delivery from Heparin-based Microparticles Reduces Cartilage Damage in a Rat Model of Osteoarthritis [C] . LE Tellier, EA Trevino, AL Brimeyer, Society for Biomaterials annual meeting and exposition . 2018

机译：从肝素基微粒的关节内TSG-6递送减少了骨关节炎大鼠模型的软骨损伤
5. Role of the Synovial Membrane in Osteoarthritis Pathogenesis and Cartilage Repair [D] . Stefani, Robert M. 2020

机译：滑膜在骨关节炎发病机理和软骨修复中的作用
6. Remifentanil repairs cartilage damage and reduces the degradation of cartilage matrix in post-traumatic osteoarthritis and inhibits IL-1β-induced apoptosis of articular chondrocytes via inhibition of PI3K/AKT/NF-κB phosphorylation [O] . Hai Ke, Xiaping Mou, Qing Xia 2020

机译：瑞芬太尼修理软骨损伤降低了创伤后骨关节炎中软骨基质的降解并通过抑制PI3K / AKT / NF-κB磷酸化抑制IL-1β诱导的关节软骨细胞凋亡
7. Differential synovial expression patterns between patients with progression of cartilage damage and progression of osteophyte formation in early osteoarthritis [O] . Blom A.B., van den Bosch M.H., Cats H., 2015

机译：早期骨关节炎中软骨损伤进展和骨赘形成进展患者之间的滑膜表达差异

The S100A9 inhibitor paquinimod (ABR-215757) reduces synovial activation, osteophyte formation and cartilage damage in experimental osteoarthritis

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