首页> 外文OA文献 >ANNEXATM-R: A PHASE 3 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL, DEMONSTRATING REVERSAL OF RIVAROXABAN-INDUCED ANTICOAGULATION IN OLDER SUBJECTS BY ANDEXANET ALFA (PRT064445), A UNIVERSAL ANTIDOTE FOR FACTOR XA (FXA) INHIBITORS

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ANNEXATM-R: A PHASE 3 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL, DEMONSTRATING REVERSAL OF RIVAROXABAN-INDUCED ANTICOAGULATION IN OLDER SUBJECTS BY ANDEXANET ALFA (PRT064445), A UNIVERSAL ANTIDOTE FOR FACTOR XA (FXA) INHIBITORS

机译：ANNEXATM-R：第3阶段随机化，双盲，局部控制的试验，证实了利达沙班诱导的老年受试者抗凝作用的逆转由ANDEXANET ALFA（PRT064445）进行，这是因子X的通用抗药性

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Gold Alexander Michael; Crowther Mark; Levy Gallia; Lu Genmin; Leeds Janet; Barron Lee; Conley Pamela; Castillo Janice; Curnutte John; Connolly Stuart;
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1. ANNEXA (TM)-R Part 2: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Trial Demonstrating Sustained Reversal of Rivaroxaban-Induced Anticoagulation in Older Subjects by Andexanet Alfa (PRT064445), a Universal Antidote for Factor XA (FXA) Inhibitors [J] . Crowther Mark, Gold Alex, Lu Genmin, Circulation: An Official Journal of the American Heart Association . 2015 ,第23期

机译：ANNEXA（TM）-R第2部分：3期随机，双盲，安慰剂对照试验，证明瑞伐沙班诱导的老年受试者抗凝的持续逆转由Andexanet Alfa（PRT064445）（一种XA因子抑制剂（FXA）的通用解毒剂）持续进行
2. ANNEXA (TM)-A: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Trial, Demonstrating Reversal of Apixaban-Induced Anticoagulation in Older Subjects by Andexanet alfa (PRT064445), a Universal Antidote for Factor Xa (fXa) Inhibitors [J] . Crowther Mark, Levy Gallia G., Lu Genmin, Circulation: An Official Journal of the American Heart Association . 2014 ,第23期

机译：ANNEXA（TM）-A：第3阶段随机，双盲，安慰剂对照试验，证实了Adexanet alfa（PRT064445）（一种Xa因子抑制剂（fXa）的通用解毒剂）逆转了Apixaban诱导的老年患者抗凝作用。
3. ANDEXANET ALFA, A UNIVERSAL ANTIDOTE FOR REVERSAL OF ANTICOAGULATION OF FACTOR XA INHIBITORS IN HEALTHY HUMAN VOLUNTEERS [J] . Crowther Mark, Gold Alex, Lu Genmin, American Journal of Hematology . 2016 ,第9期

机译：ANDEXANET ALFA，用于人体健康志愿者中XA抑制剂抑制作用的通用抗药性
4. Andexanet alfa for reversal of factor Xa inhibitors induced-anticoagulation in nonclinical and clinical studies [C] . Genmin Lu, Polly Pine, Janet Leeds, World biomaterials congress . 2016

机译：Andexanet alfa在非临床和临床研究中逆转Xa因子抑制剂诱导的抗凝作用
5. Reversal of Factor Xa Inhibitors by Andexanet Alfa May Increase Thrombogenesis Compared to Pretreatment Values [O] . Fakiha Siddiqui, Alfonso Tafur, Lorenzo Storino Ramacciotti, 2019

机译：与预处理值相比Andexanet Alfa逆转因子Xa抑制剂可能增加血栓形成
6. Andexanet alfa for reversal of factor Xa inhibitor-associated anticoagulation [O] . Elise Carpenter, Divita Singh, Eric Dietrich, 2019

机译：Andexanet Alfa逆转因子XA抑制剂相关的抗凝

ANNEXATM-R: A PHASE 3 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL, DEMONSTRATING REVERSAL OF RIVAROXABAN-INDUCED ANTICOAGULATION IN OLDER SUBJECTS BY ANDEXANET ALFA (PRT064445), A UNIVERSAL ANTIDOTE FOR FACTOR XA (FXA) INHIBITORS

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