Antisense inhibition of Bcr-Abl/c-Abl synthesis promotes telomerase activity and upregulates tankyrase in human leukemia cells11The GenBank accession numbers for human Bcr-Abl and human c-Abl cDNA sequences described in this paper are X02596/M24603 and X16416, respectively. ODN1/PS-ODN1 antisense sequences and ODN3/PS-ODN3 control sense sequences correspond to the nucleotide sites localized in the breakpoint cluster region (b3a2 junction) in the 9:22 chromosomal translocation (Philadelphia chromosome, accession numbers X02596 and M24603, version X02596.1, between ex. 3061 and 3121). ODN2/PS-ODN2 antisense sequences and ODN4/PS-ODN4 control sense sequences correspond to the nucleotide site of Abl proto-oncogene, localized between ex. 961 and 1021 (accession number X16416, version X16416.1). ODN5 and PS-ODN5 are nonsense sequences and did not show homology with both cDNAs.