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O2-independent damage of cytochrome P450 by CCl4-metabolites in hepatic microsomes

机译：肝微粒体中CCl4-代谢物对O2的O2依赖性损伤对细胞色素P450的损害

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Groot Herbert De; Haas Wolfgang;
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年度 1980
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1. O2‐independent damage of cytochrome P450 by CCl4‐metabolites in hepatic microsomes [J] . Groot Herbert De, Haas Wolfgang FEBS Letters . 1980,第2期

机译：肝微粒体中CCl4代谢物对细胞色素P450的O2非依赖性损伤
2. Cytochrome P450 1A1 (CYP1A1) Inhibitor α-Naphthoflavone Interferes with UDP-Glucuronosyltransferase (UGT) Activity in Intact but Not in Permeabilized Hepatic Microsomes from 3-Methylcholanthrene-Treated Rats: Possible Involvement of UGT-P450 Interac [J] . Ken-ichiro Taura, Eri Naito, Yuji Ishii, Biological & pharmaceutical bulletin . 2004,第1期

机译：细胞色素P450 1A1（CYP1A1）抑制剂α-萘黄酮干扰UDP-葡萄糖醛酸转移酶（UGT）的活性，但对3甲基胆碱处理大鼠的透化肝微粒体没有影响：UGT-P450 Interac可能参与了
3. The Anticancer Drug Ellipticine Activated with Cytochrome P450 Mediates DNA Damage Determining Its Pharmacological Efficiencies: Studies with Rats, Hepatic Cytochrome P450 Reductase Null (HRN™) Mice and Pure Enzymes [J] . Eva Frei, Guillermo T. S#xE1, ez, International Journal of Molecular Sciences . 2014,第1期

机译：细胞色素P450激活的抗癌玫瑰树碱介导DNA损伤，从而确定其药理效率：与大鼠，肝细胞色素P450还原酶无效（HRN™）小鼠和纯酶的研究
4. Identification of Rilpivirine Metabolites in Human Liver Microsomes and Characterization of Cytochrome P450 Enzymes Involved in the Biotransformation by LC-MS/MS [C] . Josiane de Oliveira Cardoso, Jessica Bo Li Lu, Regina Vincenzi Oliveira, ASMS Conference on Mass Spectrometry and Allied Topics . 2014

机译：LC-MS / MS中，LC-MS / MS中患者肝脏微粒体中瑞培代谢产物的鉴定及涉及生物转化的细胞色素P450酶的表征
5. System-dependent metabolism of drugs by cytochrome P450: The mechanistic basis for why human liver microsomes are superior to human hepatocytes at metabolizing midazolam but inferior at metabolizing desloratadine [D] . Kazmi, Faraz 2015

机译：细胞色素P450对系统的药物依赖性代谢：为什么人肝微粒体在代谢咪达唑仑时要优于人肝细胞，而在地氯雷他定的代谢时却不如人肝细胞的机理基础
6. The Anticancer Drug Ellipticine Activated with Cytochrome P450 Mediates DNA Damage Determining Its Pharmacological Efficiencies: Studies with Rats Hepatic Cytochrome P450 Reductase Null (HRN™) Mice and Pure Enzymes [O] . Marie Stiborová, Věra Černá, Michaela Moserová, 2015

机译：细胞色素P450激活的抗癌药玫瑰树碱介导DNA损伤确定其药理效率：对大鼠肝细胞色素P450还原酶无效（HRN™）小鼠和纯酶的研究
7. Human hepatic and renal microsomes, cytochromes P450 1A1/2, NADPH:Cytochrome P450 reductase and prostaglandin H synthase mediate the formation of aristolochic acid-DNA adducts found in patients with urothelial cancer [O] . Marie Stiborová, Eva Frei, Petr Hodek, 2004

机译：人类肝和肾微粒体，细胞学瘤P450 1A1 / 2，NADPH：细胞色素P450还原酶和前列腺素H合成酶介导在尿路上癌症患者中发现的特洛代洛酸-DNA加合物的形成

O2-independent damage of cytochrome P450 by CCl4-metabolites in hepatic microsomes

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