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Mutations of the central tyrosines of putative cholesterol recognition amino acid consensus (CRAC) sequences modify folding, activity, and sterol-sensing of the human ABCG2 multidrug transporter

机译：假定胆固醇识别氨基酸共有（CRAC）序列的中央酪氨酸的突变会修饰人ABCG2多药转运蛋白的折叠，活性和固醇感

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Gál Zita; Hegedüs Csilla; Szakács Gergely; Váradi András; Sarkadi Balázs; Özvegy-Laczka Csilla;
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1. Mutations of the central tyrosines of putative cholesterol recognition amino acid consensus (CRAC) sequences modify folding, activity, and sterol-sensing of the human ABCG2 multidrug transporter [J] . Gal Zita, Hegedues Csilla, Szakacs Gergely, Biochimica et biophysica acta. Biomembranes . 2015,第2期

机译：假定胆固醇识别氨基酸共有（CRAC）序列的中央酪氨酸的突变修饰人ABCG2多药转运蛋白的折叠，活性和固醇感。
2. Regulation of the function of the human ABCG2 multidrug transporter by cholesterol and bile acids: Effects of mutations in potential substrate and steroid binding sites [J] . Telbiszá., HegedüsC., VáradiA., Drug Metabolism and Disposition: The Biological Fate of Chemicals . 2014,第4期

机译：胆固醇和胆汁酸对人ABCG2多药转运蛋白功能的调节：潜在底物和类固醇结合位点突变的影响
3. Cholesterol binding at the cholesterol recognition/ interaction amino acid consensus (CRAC) of the peripheral-type benzodiazepine receptor and inhibition of steroidogenesis by an HIV TAT-CRAC peptide [J] . Hua Li, Zhi-xing Yao, Babett Degenhardt Proceedings of the National Academy of Sciences of the United States of America . 2001,第3期

机译：胆固醇结合在外周型苯并二氮杂cholesterol受体的胆固醇识别/相互作用氨基酸共有（CRAC）处，并通过HIV TAT-CRAC肽抑制类固醇生成
4. Humanized Recombinant Vaccinia Virus Complement Control Protein (hrVCP) with Three Amino Acid Changes, H98Y, E102K, and E120K Creating an Additional Putative Heparin Binding Site, Is 100-fold More Active Than rVCP in Blocking Both Classical and Alternative Complement Pathways [C] . YOHANNES T. GHEBREMARIAM, ODUTAYO O. ODUNUGA, KRISTEN JANSE, International Conference on Natural Products and Molecular Medicine . 2005

机译：人源化重组疫苗病毒补蛋白（HRVCP）具有三个氨基酸变化，H98Y，E102K和E120K产生另外的肝素结合位点，比RVCP在阻断经典和替代的补体途径时，100倍。
5. Developing Peptide Therapeutics that Inhibit Bacterial Toxins Utilizing a Cholesterol Recognition Amino Acid Consensus (CRAC) Motif [D] . Koufos, Evan 2018

机译：利用胆固醇识别氨基酸共识（CRAC）主题开发抑制细菌毒素的肽疗法
6. Cholesterol binding at the cholesterol recognition/ interaction amino acid consensus (CRAC) of the peripheral-type benzodiazepine receptor and inhibition of steroidogenesis by an HIV TAT-CRAC peptide [O] . Hua Li, Zhi-xing Yao, Babett Degenhardt, 2001

机译：胆固醇结合胆固醇的识别/相互作用氨基酸共有（CRAC）外周型苯并二氮杂receptor受体及其抑制作用 HIV TAT-CRAC肽类固醇生成
7. Regulation of the Function of the Human ABCG2 Multidrug Transporter by Cholesterol and Bile Acids: Effects of Mutations in Potential Substrate- And Steroid-Binding Sites. [O] . Telbisz, Ágnes, Hegedűs, Csilla, Váradi, András, 2014

机译：胆固醇和胆汁酸对人ABCG2多药转运蛋白功能的调节：潜在底物和类固醇结合位点的突变的影响。

Mutations of the central tyrosines of putative cholesterol recognition amino acid consensus (CRAC) sequences modify folding, activity, and sterol-sensing of the human ABCG2 multidrug transporter

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