首页> 外文OA文献 >Pharmacologic Expansion of Donor-Derived, Naturally Occurring CD4+Foxp3+ Regulatory T Cells Reduces Acute Graft-versus-Host Disease Lethality Without Abrogating the Graft-versus-Leukemia Effect in Murine Models

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Pharmacologic Expansion of Donor-Derived, Naturally Occurring CD4+Foxp3+ Regulatory T Cells Reduces Acute Graft-versus-Host Disease Lethality Without Abrogating the Graft-versus-Leukemia Effect in Murine Models

机译：供体来源的自然产生的CD4 + Foxp3 +调节性T细胞的药理学扩展可降低急性移植物抗宿主疾病的致死率，而不会减慢鼠模型中的移植物抗白血病作用

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Duramad Omar; Laysang Amy; Li Jun; Ishii Yasuyuki; Namikawa Reiko;
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1. Pharmacologic expansion of donor-derived, naturally occurring CD4(+)Foxp3(+) regulatory T cells reduces acute graft-versus-host disease lethality without abrogating the graft-versus-leukemia effect in murine models. [J] . Duramad O, Laysang A, Li J, Biology of blood and marrow transplantation: journal of the American Society for Blood and Marrow Transplantation . 2011,第8期

机译：供体来源的，天然存在的CD4（+）Foxp3（+）调节性T细胞的药理学扩展可降低急性移植物抗宿主疾病的致死率，而不会废除小鼠模型中的移植物抗白血病作用。
2. Rapamycin and IL-2 reduce lethal acute graft-versus-host disease associated with increased expansion of donor type CD4+CD25+Foxp3+ regulatory T cells. [J] . Shin HJ, Baker J, Leveson Gower DB, Blood: The Journal of the American Society of Hematology . 2011,第8期

机译：雷帕霉素和IL-2可减少致死性急性移植物抗宿主病，这种疾病与供体CD4 + CD25 + Foxp3 +调节性T细胞的扩增增加有关。
3. Clinical-Grade–Expanded Regulatory T Cells Prevent Graft-versus-Host Disease While Allowing a Powerful T Cell–Dependent Graft-versus-Leukemia Effect in Murine Models [J] . Beatrice Del Papa, Loredana Ruggeri, Elena Urbani, Biology of blood and marrow transplantation: journal of the American Society for Blood and Marrow Transplantation . 2017,第11期

机译：临床级扩张的调节性T细胞防止移植物与宿主疾病，同时允许在鼠模型中允许强大的T细胞依赖性移植物 - 白血病效应
4. Clonal expansion of V-delta-1 Tcells in acute graft-versus-host disease [C] . Yoh Ishiguro, Hideki Takami, Akihiro Munakata Hirosaki Transplantation Research Project . 2000

机译：急性移植物与宿主疾病中V-Delta-1 T细胞的克隆扩增
5. ST2/MyD88 Signaling Is a Therapeutic Target Alleviating Murine Acute Graft-Versus-Host Disease Sparing T Regulatory Cell Function [D] . Griesenauer, Brad. 2018

机译：ST2 / MyD88信号传导是减轻小鼠急性移植物抗宿主病的T调节细胞功能的治疗靶标。
6. Rapamycin and IL-2 reduce lethal acute graft-versus-host disease associated with increased expansion of donor type CD4+CD25+Foxp3+ regulatory T cells [O] . Ho-Jin Shin, Jeanette Baker, Dennis B. Leveson-Gower, -1

机译：雷帕霉素和IL-2减少致命的急性移植物抗宿主病与供体CD4 + CD25 + Foxp3 +调节性T细胞扩增增加有关
7. CD4+ Invariant Natural Killer T Cells Protect from Acute Graft-Versus-Host Disease Lethality through a Dramatic Expansion of Donor-Derived CD4+FoxP3+ Regulatory T Cells [O] . Schneidawind Dominik, Pierini Antonio, Alvarez Maite, 2014

机译：CD4 +不变的自然杀伤性T细胞通过急剧扩增供体来源的CD4 + FoxP3 +调节性T细胞来保护免受急性移植物抗宿主病的致命性

Pharmacologic Expansion of Donor-Derived, Naturally Occurring CD4+Foxp3+ Regulatory T Cells Reduces Acute Graft-versus-Host Disease Lethality Without Abrogating the Graft-versus-Leukemia Effect in Murine Models

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