Flow perfusion culture is used in many areas of tissue engineering and offers several key advantages. However,one challenge to these cultures is the relatively low-throughput nature of perfusion bioreactors. Here, a flowperfusion bioreactor with increased throughput was designed and built for tissue engineering. This design usesan integrated medium reservoir and flow chamber in order to increase the throughput, limit the volume ofmedium required to operate the system, and simplify the assembly and operation.
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