Designing patient-specific melt-electrospun scaffolds for bone regeneration

摘要

This thesis developed a method for designing 3D printed implants to restore bone loss. Using melt-electrospinning 3D printing technology and patient medical scan data, the researcher designed and fabricated anatomically-accurate scaffolds using biodegradable polymers to ultimately facilitate bone regeneration. The method presented was applied to three clinically-relevant case studies and can now be used for the design of a range of other implants based on patient scan data. The application and importance of this method was discussed as a key element in the biofabrication process for the fabrication of biologically-relevant, patient-specific human tissues and organs.