Biologically guided adaptive radiotherapy treatment planning for virally-mediated head and neck cancer

摘要

This thesis developed predictive models and risk profiles for pre-treatment identification of suitable adaptive radiotherapy candidates, from a cohort of oropharyngeal and nasopharyngeal cancer patients. This unique prospective approach could facilitate effective implementation of head and neck cancer adaptive radiotherapy into radiotherapy departments in Australia and internationally, through forward planning and appropriate resource allocation. Predicting those patients more likely to need adaptive radiotherapy in an efficient and judicious manner provides numerous benefits to radiotherapy departments across the world and ultimately, the patients under our care.