We determined the influence of adaptive optics correction on through-focus illiterate-E visual acuity and through-focus contrast sensitivity under monochromatic conditions. In two subjects, adaptive optics improved high and low (12 %) contrast in-focus visual acuity by 0.1 to 0.15 logMAR, but resulted in more rapid and more symmetrical deterioration in visual acuity away from in-focus. In one subject, adaptive optics improved in-focus contrast sensitivity and resulted in more symmetrical and greater loss of contrast sensitivity about the peak sensitivity because of correction of higher order aberrations. The results show that full correction of higher order aberrations may worsen spatial visual performance in the presence of some defocus.
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