'Pure shift' 1H NMR, a robust method for revealing heteronuclear couplings in complex spectra.

摘要

We investigate the utility of “pure shift” techniques in revealing heteronuclear couplings inudcomplex 1H NMR spectra. The results show the technique to be a robust and valuableudcomplement to the standard 1H spectrum, and an attractive alternative to heteronuclearuddecoupling since the technique is independent of the size of the heteronuclear couplings andudthe chemical shift range(s) of the heteronuclei involved. We highlight some possible artefacts,udand the subtle effects due to the presence of 13C nuclei in otherwise symmetric molecules whenudbilinear rotational decoupling (BIRD) elements are present in the pulse sequence.