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Imatinib induces mitochondria-dependent apoptosis of the Bcr-Abl-positive K562 cell line and its differentiation toward the erythroid lineage.

机译：伊马替尼诱导Bcr-Abl阳性K562细胞系的线粒体依赖性凋亡及其向红系谱系的分化。

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International audience

机译：国际观众

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Jacquel Arnaud; Herrant Magali; Legros Laurence; Belhacene Nathalie; Luciano Frederic; Pages Gilles; Hofman Paul; Auberger Patrick;
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年度 2003
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正文语种 eng
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专利

1. Erythropoietin overcomes imatinib-induced apoptosis and induces erythroid differentiation in TF-1/bcr-abl cells. [J] . Uchida M, Watanabe T, Kunitama M, Stem Cells . 2004,第4期

机译：促红细胞生成素克服了伊马替尼诱导的凋亡，并诱导了TF-1 / bcr-abl细胞中的类红细胞分化。
2. Erythroid Differentiation Sensitizes K562 Leukemia Cells to TRAIL-Induced Apoptosis by Downregulation of c-FLIP [J] . Ville Hietakangas, Minna Poukkula, Kaisa M. Heiskanen, Molecular and Cellular Biology . 2003,第4期

机译：红细胞分化通过下调c-FLIP刺激K562白血病细胞对TRAIL诱导的细胞凋亡
3. Fast apoptosis and erythroid differentiation induced by imatinib mesylate in JURL-MK1 cells. [J] . Kuzelova K, Grebenova D, Marinov I, Journal of cellular biochemistry. . 2005,第2期

机译：甲磺酸伊马替尼在JURL-MK1细胞中诱导快速凋亡和红系分化。
4. Mitochondria-dependent apoptosis in HeLa cell induced by methylene blue-mediated photodynamic therapy [C] . Lu Yan, Chen Xiao-Ping, Shen Ping-Ping International Symposium on Medical and Pharmaceutical Biotechnology(医药生物技术国际研讨会) . 2009

机译：亚甲基蓝介导的光动力疗法诱导HeLa细胞线粒体依赖性凋亡
5. Aberrant subcellular targeting of the G185R neutrophil elastase mutant associated with severe congenital neutropenia induces premature apoptosis of differentiating promyelocytes, and, Expression and function of the transient receptor potential 2 (TRPM2) ion channel in dendritic cells. [D] . Massullo, Pam. 2007

机译：与严重的先天性中性粒细胞减少症相关的G185R中性粒细胞弹性蛋白酶突变体的异常亚细胞靶向诱导分化的早幼粒细胞的过早凋亡，以及树突状细胞中瞬时受体电位2（TRPM2）离子通道的表达和功能。
6. Correction: Wogonin induces cell cycle arrest and erythroid differentiation in imatinib-resistant K562 cells and primary CML cells [O] . Hao Yang, Hui Hui, Qian Wang, 2020

机译：更正：Wogonin在抗伊马替尼的K562细胞和原代CML细胞中诱导细胞周期停滞和红系分化
7. Imatinib induces mitochondria-dependent apoptosis of the Bcr-Abl-positive K562 cell line and its differentiation toward the erythroid lineage. [O] . Jacquel Arnaud, Herrant Magali, Legros Laurence, 2003

机译：伊马替尼诱导Bcr-Abl阳性K562细胞系的线粒体依赖性凋亡及其向红系谱系的分化。

Imatinib induces mitochondria-dependent apoptosis of the Bcr-Abl-positive K562 cell line and its differentiation toward the erythroid lineage.

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