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Interaction of novel positive allosteric modulators of metabotropic glutamate receptor 5 with the negative allosteric antagonist site is required for potentiation of receptor responses.

机译：代谢型谷氨酸受体5的新型正变构调节剂与负变构拮抗剂位点的相互作用是增强受体反应所必需的。

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International audience

机译：国际观众

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作者
Chen Yelin; Nong Yi; Goudet Cyril; Hemstapat Kamondanai; De Paulis Tomas; Pin Jean-Philippe; Conn P Jeffrey;
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年度 2007
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正文语种 eng
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1. Interaction of novel positive allosteric modulators of metabotropic glutamate receptor 5 with the negative allosteric antagonist site is required for potentiation of receptor responses. [J] . Chen Y, Nong Y, Goudet C, Molecular pharmacology. . 2007,第5期

机译：代谢反应型谷氨酸受体5的新型正变构调节剂与负变构拮抗剂位点的相互作用是增强受体反应所必需的。
2. Chemical switch of a metabotropic glutamate receptor 2 silent allosteric modulator into dual metabotropic glutamate receptor 2/3 negative/positive allosteric modulators [J] . Schann S., Mayer S., Franchet C., Journal of Medicinal Chemistry . 2010,第24期

机译：代谢型谷氨酸受体2沉默变构调节剂化学转化为双重代谢型谷氨酸受体2/3负/正变构调节剂
3. A Novel Class of Positive Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 1 Interact with a Site Distinct from That of Negative Allosteric Modulators [J] . Kamondanai Hemstapat Molecular pharmacology. . 2006,第2期

机译：新型的代谢型谷氨酸受体亚型1的正变构调节剂与不同于负变构调节剂的位点相互作用
4. IDENTIFICATION OF NADPH-INDEPENDENT GSH CONJUGATES OF ACETYLENE-CONTAINING POSITIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR SUBTYPE 5 [C] . Xiaoliang Zhuo, Xiaohua Huang, Andrew Degnan, ASMS Conference on Mass Spectrometry and Allied Topics . 2014

机译：鉴定含乙炔谷氨酸受体亚型5的含乙炔的阳性变构调节剂的NADPH-无关的GSH缀合物
5. Effects of a metabotropic glutamate receptor 5 positive allosteric modulator, CDPPB, on spatial learning in rodents. [D] . Fowler, Stephanie Wade. 2013

机译：代谢型谷氨酸受体5阳性变构调节剂CDPPB对啮齿类动物空间学习的影响。
6. Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4): Part I. Discovery of pyrazolo34-dpyrimidines as novel mGluR4 positive allosteric modulators [O] . Colleen M. Niswender, Evan P. Lebois, Qingwei Luo, -1

机译：代谢型谷氨酸受体亚型4（mGluR4）的正变构调节剂：第一部分。吡唑并34-d嘧啶作为新型mGluR4正变构调节剂的发现
7. Interaction of novel positive allosteric modulators of metabotropic glutamate receptor 5 with the negative allosteric antagonist site is required for potentiation of receptor responses. [O] . Chen Yelin, Nong Yi, Goudet Cyril, 2007

机译：代谢型谷氨酸受体5的新型正变构调节剂与负变构拮抗剂位点的相互作用是增强受体反应所必需的。

Interaction of novel positive allosteric modulators of metabotropic glutamate receptor 5 with the negative allosteric antagonist site is required for potentiation of receptor responses.

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