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A recombinant trispecific single-chain Fv derivative directed against CD123 and CD33 mediates effective elimination of acute myeloid leukaemia cells by dual targeting

机译：针对CD123和CD33的重组三特异性单链Fv衍生物通过双重靶向介导有效消除急性髓样白血病细胞

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International audience

机译：国际观众

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Kügler, Markus; Stein, Christoph; Kellner, Christian; Mentz, Kristin; Saul, Domenica; Schwenkert, Michael; Schubert, Ingo; Singer, Heiko; Oduncu, Fuat; Stockmeyer, Bernard; Mackensen, Anreas; Fey, G;
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年度 2010
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正文语种 en
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1. A recombinant trispecific single-chain Fv derivative directed against CD123 and CD33 mediates effective elimination of acute myeloid leukaemia cells by dual targeting. [J] . Kugler M, Stein C, Kellner C, British Journal of Haematology . 2010,第5期

机译：针对CD123和CD33的重组三特异性单链Fv衍生物通过双重靶向介导有效消除急性髓细胞性白血病细胞。
2. A recombinant trispecific single-chain Fv derivative directed against CD123 and CD33 mediates effective elimination of acute myeloid leukaemia cells by dual targeting [J] . Markus Kügler, Christoph Stein, Christian Kellner, British Journal of Haematology . 2010,第5期

机译：针对CD123和CD33的重组三特异性单链Fv衍生物通过双重靶向介导有效消除急性髓性白血病细胞
3. Novel conjugates of single-chain Fv antibody fragments specific for stem cell antigen CD123 mediate potent death of acute myeloid leukaemia cells [J] . Christoph Stein, Christian Kellner, Markus Kugler British Journal of Haematology . 2010,第6期

机译：对干细胞抗原CD123具有特异性的单链Fv抗体片段的新型缀合物介导急性髓样白血病细胞的有效死亡
4. A single-chain triplebody with specificity for CD19 and CD33 mediates effective lysis of mixed lineage leukemia cells by dual targeting [O] . Ingo Schubert, Christian Kellner, Christoph Stein, 2011

机译：具有CD19和CD33特异性的单链三聚体通过双重靶向介导混合谱系白血病细胞的有效裂解
5. A single-chain triplebody with specificity for CD19 and CD33 mediates effective lysis of mixed lineage leukemia cells by dual targeting [O] . Schubert, Ingo, Kellner, Christian, Stein, Christoph, 2011

机译：具有CD19和CD33特异性的单链三聚体通过双重靶向介导混合谱系白血病细胞的有效裂解

A recombinant trispecific single-chain Fv derivative directed against CD123 and CD33 mediates effective elimination of acute myeloid leukaemia cells by dual targeting

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