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Development of an antimicrobial blended white LED system containing pulsed 405-nm LEDs for decontamination applications

机译:开发用于杀菌应用的包含脉冲405 nm LED的抗菌混合白光LED系统

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摘要

This study details the design, build and testing of a prototype antimicrobial blended white light unit containing pulsed red, yellow, green and 405nm LEDs. With a push for alternative methods of disinfection, optical methods have become a topic of interest. Ultra-violet (UV) light is widely known for its antimicrobial properties however; 405nm light has demonstrated significant antimicrobial properties against many common hospital acquired pathogens. In this study, a pulsed, blended, white-light prototype with a high content of 405 nm antimicrobial light, was designed, built and tested. Antimicrobial efficacy testing of the prototype was conducted using Staphylococcus aureus and Pseudomonas. aeruginosa, two bacteria which are common causes of hospital acquired infections. These were exposure to 3 different light outputs from the prototype and the surviving bacteria enumerated. Results showed that the mixed light output provided a much better CRI and light output under which to work. Also, the light output containing 405 nm light provided an antimicrobial effect, with decontamination of 103 CFUml-1 populations of both bacterial species. The other light content (red, yellow, green) had no beneficial or adverse effects on the antimicrobial properties of the 405nm light. The results suggest that with further development, it could be possible to produce an antimicrobial blended white light containing pulsed 405nm light that could supplement or even replace standard white lighting in certain environments.
机译:这项研究详细介绍了包含脉冲红,黄,绿和405nm LED的原型抗菌混合白光单元的设计,构建和测试。随着替代消毒方法的推动,光学方法已成为人们关注的话题。紫外线(UV)因其抗菌特性而广为人知。 405nm的光对许多常见的医院获得的病原体具有显着的抗菌性能。在这项研究中,设计,制造和测试了具有高含量405 nm抗菌光的脉冲混合白光原型。使用金黄色葡萄球菌和假单胞菌进行了原型的抗菌功效测试。铜绿菌,这两种细菌是医院获得性感染的常见原因。这些样品暴露于来自原型的3种不同的光输出,并列举了存活的细菌。结果表明,混合光输出提供了更好的CRI和工作时的光输出。同样,包含405 nm光的光输出提供了抗菌效果,对这两种细菌的​​103 CFUml-1种群进行了净化。其他光含量(红色,黄色,绿色)对405nm光的抗菌特性没有有利或不利的影响。结果表明,随着进一步的发展,有可能产生一种包含405nm脉冲光的抗菌混合白光,它可以在某些环境中补充甚至替代标准白光。

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