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High-throughput micromixers based on acoustic streaming induced by surface acoustic wave

机译:基于表面声波引起的声流的高通量微混合器

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摘要

Flow characteristics in microfluidic devices is naturally laminar due to the small channel dimensions. Mixing based on molecular diffusion is generally poor. In this article, we report the fabrication and characterization of active surface-acousticwave-driven micromixers which exploit the acoustic streaming effect to significantly improve the mixing efficiency. A side-by-side flow of water and fluorescent dye solution was driven by a syringe pump. Surface wave with a frequency of 13 MHz was launched perpendicular to the flow. The wave was generated by two designs of interdigitated electrodes on LiNbO3 substrate: parallel electrodes and focusing electrodes. The mixing efficiency was observed to be proportional to the square of the applied voltage. Under the same applied voltage, the focusing type offers a better mixing efficiency. The fabrication of the micromixer is compatible to current technology such as soft lithography and deep reactive ion etching. Despite the high throughput and fast mixing time, the mixer design is simple and could be integrated into any microfluidic platform.
机译:由于小通道尺寸,微流体装置中的流动特性自然是层流的。基于分子扩散的混合通常较差。在本文中,我们报告了有源表面声波驱动的微型混合器的制造和特性,这些微型混合器利用了声流效应来显着提高混合效率。水和荧光染料溶液的并排流动由注射泵驱动。垂直于流动方向发射频率为13 MHz的表面波。该波是由LiNbO3基板上的叉指式电极的两种设计产生的:平行电极和聚焦电极。观察到混合效率与施加电压的平方成正比。在相同的施加电压下,聚焦型可提供更好的混合效率。微型混合器的制造与当前技术兼容,例如软光刻和深反应离子刻蚀。尽管产量高,混合时间快,但混合器的设计仍很简单,可以集成到任何微流体平台中。

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