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A Simplified Computational Method for Overall Risk Probability in Probabilistic Health Risk Assessments of Environmental Pollutants

机译:环境污染物概率健康风险评估中总体风险概率的简化计算方法

摘要

In the assessment of health risks of environmental pollutants, both conventional methods and probabilistic methods based on the use of cumulative probability plots have been used. Probabilistic risk assessment has the advantage that the statistical distributions of both the exposure data set and the adverse effect data set are taken into account in risk characterization. In addition, the method of overall risk probability (ORP) has been used to quantify the overall risk probability of adverse effects for the population samples. The disadvantage is that many more data points are needed to obtain the cumulative probability plots and the calculation of the ORP from the probability plots is more complicated. In this paper, a simplified computational method for the estimation of the ORP was developed. In this method, an overall risk factor (ORF), as an estimated value of the ORP value, was obtained from the mid-point of an exposure exceedence curve. The ORF can also be obtained from an inversed cumulative probability plot of the exposure curve, thus eliminating the needs for the use of the exposure exceedence curve and the numerical integration of the exceedence curve in ORP computation. The use of ORF method was illustrated with a practical example and the results indicated that the values of the ORF and ORP are about the same.
机译:在评估环境污染物的健康风险时,既使用了传统方法,又使用了基于累积概率图的概率方法。概率风险评估的优势在于,在风险表征中要考虑暴露数据集和不利影响数据集的统计分布。此外,总体风险概率(ORP)方法已用于量化总体样本不利影响的总体风险概率。缺点是需要更多的数据点才能获得累积概率图,并且根据概率图计算ORP更为复杂。本文提出了一种简化的ORP估算方法。在该方法中,从暴露率超过曲线的中点获得了总体风险因子(ORF),作为ORP值的估计值。还可以从曝光曲线的逆累积概率图获得ORF,从而消除了在ORP计算中使用曝光超出曲线和超出曲线的数值积分的需求。通过一个实例说明了ORF方法的使用,结果表明ORF和ORP的值大致相同。

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