Synthesis of thiodisaccharides by photoinduced hydrothiolation of 2-acetoxy glycals

摘要

Here, we present the synthesis of α-D-galactopyranosyl and α-L-fucopyranosyl thiodisaccharides 5-8 by the photoinitiated thiol-ene reactions of 2-acetoxy-3,4,6-tri-O-acetyl-D-galactal 1 and 2-acetoxy-3,4-di-O-acetyl-L-fucal 2 with thiols 3 and 4.