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Claudin-4 Overexpression in Epithelial Ovarian Cancer Is Associated with Hypomethylation and Is a Potential Target for Modulation of Tight Junction Barrier Function Using a C-Terminal Fragment of Clostridium perfringens Enterotoxin1

机译：Claudin-4在上皮性卵巢癌中的过表达与低甲基化有关，并且是使用产气荚膜梭状芽孢杆菌肠毒素1的C端片段调节紧密连接障碍功能的潜在靶标。

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Litkouhi, Babak; Kwong, Joseph; Lo, Chun-Min; Smedley, James G; McClane, Bruce A; Aponte, Margarita; Gao, Zhijian; Sarno, Jennifer L; Hinners, Jennifer; Welch, William R; Berkowitz, Ross S; Mok, Samuel C; Garner, Elizabeth I O;
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年度 2007
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1. Mutated C-terminal fragments of Clostridium perfringens enterotoxin have increased affinity to claudin-4 and reversibly modulate tight junctions in vitro. [J] . Takahashi A, Kondoh M, Uchida H, Biochemical and Biophysical Research Communications . 2011,第3期

机译：产气荚膜梭菌肠毒素的突变C端片段增加了对claudin-4的亲和力，并在体外可逆地调节紧密连接。
2. Role of tyrosine residues in modulation of claudin-4 by the C-terminal fragment of Clostridium perfringens enterotoxin. [J] . Harada M, Kondoh M, Ebihara C, Biochemical Pharmacology . 2007,第2期

机译：酪氨酸残基在产气荚膜梭菌肠毒素C末端片段对claudin-4的调节中的作用。
3. Domain mapping of a claudin-4 modulator, the C-terminal region of C-terminal fragment of Clostridium perfringens enterotoxin, by site-directed mutagenesis. [J] . Takahashi A, Komiya E, Kakutani H, Biochemical Pharmacology . 2008,第8期

机译：通过定点诱变，claudin-4调节剂（产气荚膜梭菌肠毒素的C末端片段的C末端区域的C末端区域）的结构域作图。
4. Interleukin -1beta (IL-1β) modulation of intestinal epithelial tight junction barrier [D] . Al-Sadi, Rana M. 2007

机译：白细胞介素-1β（IL-1β）对肠上皮紧密连接屏障的调节
5. Claudin-4 Overexpression in Epithelial Ovarian Cancer Is Associated with Hypomethylation and Is a Potential Target for Modulation of Tight Junction Barrier Function Using a C-Terminal Fragment of Clostridium perfringens Enterotoxin [O] . Babak Litkouhi, Joseph Kwong, Chun-Min Lo, 2007

机译：Claudin-4在上皮性卵巢癌中的过表达与低甲基化有关并且是使用产气荚膜梭菌肠毒素C末端片段调节紧密连接屏障功能的潜在靶标
6. Claudin-4 Overexpression in Epithelial Ovarian Cancer Is Associated with Hypomethylation and Is a Potential Target for Modulation of Tight Junction Barrier Function Using a C-Terminal Fragment of Clostridium perfringens Enterotoxin [O] . Babak Litkouhi, Joseph Kwong, Chun-Min Lot, 2007

机译：Claudin-4在上皮性卵巢癌中的过度表达与低甲基化相关，并且是使用产气荚膜梭菌肠毒素的C末端片段调节紧密连接障碍功能的潜在靶标

Claudin-4 Overexpression in Epithelial Ovarian Cancer Is Associated with Hypomethylation and Is a Potential Target for Modulation of Tight Junction Barrier Function Using a C-Terminal Fragment of Clostridium perfringens Enterotoxin1

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