New Method for Monitoring Programmed Cell Death and Differentiation in Submerged Streptomyces Cultures▿ †

摘要

Vital stains were used in combination with fluorimetry for the elaboration of a new method to quantify Streptomyces programmed cell death, one of the key events in Streptomyces differentiation. The experimental approach described opens the possibility of designing online protocols for automatic monitoring of industrial fermentations.