Utility of Molecular Identification in Opportunistic Mycotic Infections: a Case of Cutaneous Alternaria infectoria Infection in a Cardiac Transplant Recipient

摘要

We report on a case of cutaneous infection caused by Alternaria infectoria in a cardiac transplant recipient. A rapid molecular diagnosis was obtained by sequence analysis of the internal transcribed spacer domain of the 5.8S ribosomal DNA region amplified from colonies developed on Sabouraud medium. Treatment consisted of a combination of systemic antifungal therapy, first with amphotericin B and then with itraconazole.