Pharmacodynamics and pharmacokinetics of BAY x 7195 aerosol, a new and selective receptor antagonist of cysteinyl-leukotrienes, in normal volunteers

摘要

1The safety, tolerability and pharmacokinetics of BAY x 7195 aerosol, a new selective receptor antagonist of cysteinyl-leukotrienes, were investigated in healthy male volunteers in two observational studies (1 and 2 mg; n=5 each) and two double blind, placebo-controlled two way crossover studies (4 and 8 mg; n=6 each) using the commercially available Inhaler Ingelheim M.