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Decision making in kidney paired donation programs with altruistic donors

机译:利他捐赠者的肾脏配对捐赠计划中的决策

摘要

In recent years, kidney paired donation has been extended to include living non-directed or altruistic donors, in which an altruistic donor donates to the candidate of an incompatible donorcandidate pair with the understanding that the donor in that pair will further donate to the candidate of a second pair, and so on; such a process continues and thus forms an altruistic donor-initiated chain. In this paper, we propose a novel strategy to sequentially allocate the altruistic donor (or bridge donor) so as to maximize the expected utility; analogous to the way a computer plays chess, the idea is to evaluate different allocations for each altruistic donor (or bridge donor) by looking several moves ahead in a derived look-ahead search tree. Simulation studies are provided to illustrate and evaluate our proposed method.
机译:近年来,肾脏配对捐赠已扩大到包括活着的非定向或无私捐赠者,其中无私捐赠者向不兼容的捐赠者候选人对的候选人捐赠,但前提是该配对中的捐赠者将进一步捐赠给无偿捐赠者候选人。第二对,依此类推;这样的过程继续进行,因此形成了利他的捐助者发起的链。在本文中,我们提出了一种新颖的策略来按顺序分配无私的捐助者(或桥梁捐助者),以最大化预期的效用。类似于计算机下棋的方式,其思想是通过在派生的前瞻搜索树中向前看几步,来评估每个利他捐赠者(或桥梁捐赠者)的不同分配。提供仿真研究来说明和评估我们提出的方法。

著录项

  • 作者

    Li Yijiang;

  • 作者单位
  • 年度 2014
  • 总页数
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类

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