Realization of a soft-MI electrospun scaffold forudtissue engineering applications

摘要

The fabrication of bioactive scaffolds able to mimic theudin vivo cellular microenvironment represents a challenge for tissueudengineering (TE). In the present work, we propose the combinationudof electrospinning (ESP) and soft-molecular imprinting (soft-MI) [1]udto create a soft-molecular imprinted fibrous scaffold for TE applications.udBy combining these techniques, we fabricated poly-L-lactideudacid (PLLA), PolyActive (PA) and poly lactic-co-glycolic acid (PLGA)udbased scaffolds functionalized using different protein arranged ontoudthe surface.