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Cohort Profile:Nausea and vomiting during pregnancy genetics consortium (NVP Genetics Consortium)

机译:队列资料:妊娠遗传学联盟中的恶心和呕吐(NVP遗传学联盟)

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摘要

Nausea and vomiting during pregnancy (NVP), commonly known as morning sickness, is very common and is typically self-limiting. However, more severe forms and the development of hyperemesis gravidarum (HG), defined as persistent and excessive vomiting, with dehydration, ketonuria and 5% bodyweight loss,1 may lead to health consequences for the mother and the offspring exposed in utero. Despite efforts towards understanding the causes of NVP and HG, they are not well established. The NVP Genetics Consortium is an open collaborative network of researchers integrating data on NVP of women who have been pregnant at least once, with the goal of investigating NVP, NVP severity and HG. Currently, the NVP Genetics Consortium brings together data from Australia, Finland, Spain, the UK and Denmark. The Consortium is actively recruiting new members.
机译:恶心和怀孕期间的呕吐(NVP),通常称为晨吐,非常普遍,通常是自限性的。但是,更严重的形式和妊娠呕吐(HG)的发展被定义为持续和过度呕吐,伴有脱水,酮尿症和体重减轻5%以上,[1]可能对母亲和子宫内的后代造成健康后果。尽管努力了解NVP和HG的原因,但它们还没有很好的建立。 NVP遗传学协会是一个开放的研究人员协作网络,它整合了至少怀孕过一次的妇女NVP的数据,目的是调查NVP,NVP的严重程度和HG。目前,NVP遗传学联盟将来自澳大利亚,芬兰,西班牙,英国和丹麦的数据汇总在一起。财团正在积极招募新成员。

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