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Blockade of alpha v beta3 and alpha v beta5 integrins by RGD mimetics induces anoikis and not integrin-mediated death in human endothelial cells.

机译：RGD模拟物对alpha v beta3和alpha v beta5整联蛋白的阻断在人类内皮细胞中诱导了神经过敏而不是整联蛋白介导的死亡。

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International audience

机译：国际观众

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Maubant Sylvie; Saint-Dizier Dominique; Boutillon Morgane; Perron-Sierra Francoise; Casara Patrick J; Hickman John A; Tucker Gordon C; Van Obberghen-Schilling Ellen;
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年度 2006
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正文语种 eng
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1. Hypoxia induces differential expression of the integrin receptors alpha(vbeta3) and alpha(vbeta5) in cultured human endothelial cells. [J] . Walton HL, Corjay MH, Mohamed SN, Journal of cellular biochemistry. . 2000,第4期

机译：低氧诱导培养的人内皮细胞中整联蛋白受体alpha（vbeta3）和alpha（vbeta5）的差异表达。
2. Benzo(a)pyrene inhibits angiogenic factors-induced alphavbeta3 integrin expression, neovasculogenesis, and angiogenesis in human umbilical vein endothelial cells. [J] . Li CH, Cheng YW, Hsu YT, Toxicological sciences: An official journal of the Society of Toxicology . 2010,第2期

机译：苯并（a）s抑制人脐静脉内皮细胞中血管生成因子诱导的alphavbeta3整联蛋白表达，新血管生成和血管生成。
3. Polarized expression and basic fibroblast growth factor-induced down-regulation of the alpha 6 beta 4 integrin complex on human microvascular endothelial cells. [J] . Sepp NT, Cornelius LA, Romani N, The Journal of investigative dermatology. . 1995,第2期

机译：极化表达和碱性成纤维细胞生长因子诱导人微血管内皮细胞上的α6β4整合素复合物的下调。
4. Molecular design of /spl alpha//sub v//spl beta//sub 3/ integrin links to RGD grafted polyethylene provides the estimation of endothelial cell adhesion [C] . Mantero, S., Vesentini, . 2002

机译：/ spl alpha // sub v // spl beta // sub 3 /整合素与RGD接枝聚乙烯的分子设计提供了内皮细胞粘附的估计
5. Hemicellulose and vitamin-C reduce xenobiotic-induced human T-cell alpha5beta1 integrin-mediated adhesion to fibronectin. [D] . Lee, Sangwoo. 2008

机译：半纤维素和维生素C减少了异种生物诱导的人类T细胞alpha5beta1整合素介导的对纤连蛋白的粘附。
6. Modulation of RGD sequence motifs regulates disintegrin recognition of alphaIIb beta3 and alpha5 beta1 integrin complexes. Replacement of elegantin alanine-50 with proline N-terminal to the RGD sequence diminishes recognition of the alpha5 beta1 complex with restoration induced by Mn2+ cation. [O] . S Rahman, A Aitken, G Flynn, 1998

机译：RGD序列基序的调节调节αIIb beta3和α5beta1整联蛋白复合物的整联蛋白识别。用脯氨酸代替RGD序列N末端的来芬太尼丙氨酸50可以减少Mn2 +阳离子诱导的α5beta1复合物的识别。
7. Blockade of alpha v beta3 and alpha v beta5 integrins by RGD mimetics induces anoikis and not integrin-mediated death in human endothelial cells. [O] . Maubant Sylvie, Saint-Dizier Dominique, Boutillon Morgane, 2006

机译：RGD模拟物对alpha v beta3和alpha v beta5整联蛋白的阻断在人类内皮细胞中诱导了神经过敏而不是整联蛋白介导的死亡。
8. Functional Interactions Between Laminin-10, alphaV beta3 Integrin and Matrix Metalloproteinase-9 in Promoting Breast Cancer Metastasis to Bone [R] . Pouliot, N. 2005

机译：层粘连蛋白-10，αVβ3整合素和基质金属蛋白酶-9促进乳腺癌转移至骨的功能性相互作用

Blockade of alpha v beta3 and alpha v beta5 integrins by RGD mimetics induces anoikis and not integrin-mediated death in human endothelial cells.

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