A study of iopamidol (Iopamiron 370) in intravenous urography in the patients with previous adverse reactions to contrast media and history of allergy

摘要

Iopamidol (Iopamiron 370) was examined for use in intravenous urography in 37 patients who previously developed adverse reactions to conventional ionic contrast media or had a history of allergy. The patients were divided into three groups (group A1:22 patients with previous adverse reactions to contrast media, but without history of allergy, group A2:8 patients with previous adverse reactions to contrast media and with history of allergy, group B:7 patients with a history of allergy, but without experience of using contrast media. Adverse reactions to iopamidol were observed in 6 patients (one in group A1, four in group A2, one in group B) and there were no serious adverse reactions. In conclusion, iopamidol seems to be a safe contrast medium for the patients without history of allergy, but we should examine it carefully as in the case of conventional ionic contrast media.