Urinary infection of resistant gram negative bacilli--synergistic action of aminobenzyl penicillin or hetacillin and cloxacillin

摘要

There is the tendency of increase of urinary tract infection with resistant gram-negative bacilli. Aminobenzyl-PC and hetacillin (Versapen) were administrated to five cases with various urinary tract infections of resistant strains. The effective results were obtained in three cases but the alterations or superinfections were observed in two cases. The main strains of chronic urinary tract infection in Nagoya University Hospital were Klebsiella and E. coli that were highly resistant against the classical broad spectrum antibiotics. Ten cases of urinary infections with resistant gram negative bacilli were treated by AB-PC or hetacillin (Versapen) and MCI-PC. The synergistic action of AB-PC or hetacillin and MCI-PC was found in seven cases of Klebsiella, Rettgerella and Ps. aeruginosa infections. No significant side effect was observed in this series.