CLIiNICAL STUDIES ON DRIP INFUSHION DIURETIC PYELOGRAPHY WITH A 60 PER CENT DIATRIZOATE

摘要

The authors investigated 96 patients, who shopped poor visualization on routine IVP, by means of the rapid drip-infusion technique with undiluted 60 % diatrizoate 100 ml. This may be called drip-infusion diuretic pyelography (DIDP). The results were as follows. 1) Diagnostic contribution: The excellent visualization of urinary tract were obtained in about 50 % of patients in whom renal function tests were normal, in about 30 % with normal renal function but with diseases of bilateral kidneys, and in about 10 % in renal insufficiency below 40 mg/dl of BUN. In the cases over 41 mg/dl of BUN, however, high contrast nephrograms were obtained, but low contrast pyelograms. 2) Safety: Side effects such as urticaria, nausea and feeling of heat were observed in 30 of 96 cases (31.3 %), but not so serious to stop the examination. Moreover, pulse, blood presure, renal function (BUN and serum creatinine), serum electrolytes (Na, Cl and K) and hepatic function were determined before and after DIDP, and the elevation of serum K level was observed in a few cases of renal insufficiency, but rarely in other cases. 3) When IVP, DIDP and DIP were carried out in the same case in a short interval, DIDP and DIP showed fairly better contrast effect than IVP. There was no difference between DIDP and DIP, but in cases of ureteral stenosis, DIP showed somewhat better effects than DIDP. As above mentioned, we conclude that, in urography with high dose of contrast media, the satisfactory visualization of urinary tract, as in DIP, can be obtained without dilution of contrast media.