We report a case of adenocarcinoma within a female urethral diverticulum. The patient was a 54-year-old woman, with a three-month history of dysuria. On physical examination a soft, round mass was palpable in the anterior vaginal wall. Excretory urography demonstrated elevation of the bladder floor. Panendoscopy demonstrated a diverticulum at the 7 o'clock position in proximal urethra. A papillary mass confined to the diverticulum was identified and biopsied. The histopathologic findings showed adenocarcinoma. The patient underwent total cystectomy, pelvic lymphadenectomy, and creation of an ileal conduit. She was well 1 year and 5 months later.
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