Studies on Gonococcal and Non-gonococcal Urethritis Report 3 : Clinical and Experimental Studies on Gonorrhea to Several Antibiotics

摘要

I had treated 123 cases of gonorrhea for five yea r s , from 1952 to 1956 at the Urological Clinic of Kyoto University, with the use of several antibiotics. The rates of cures showed ; Streptomycin (SM) 8 5 .2 %, Chloramphenicol (CM) 100 %, Chlortetracycline (AM) 66.7 %, Oxytetracycline (TM) 87.5 %, Tetracycline (TC) 88.2 %, Erythromycin (EM) 95.5 %, and blood levels were measured respectively. I observed the sensitivity of gonococci to several antibiotics in seven strains, and found that Sonoda strain which was not cured in TC treatment resisted TC in vitro. I also observed the increase and decrease of antibiotics-resistance of gonococci in vitro.