Magnesium and magnesium alloys as degradable metallic biomaterials

摘要

Drawbacks associated with permanent metallic implants lead to the search for degradable metallic biomaterials. Magnesium has been considered as it is essential to bodies and has a high biodegradation potential. For magnesium and its alloys to be used as biodegradable implant materials, their degradation rates should be consistent with the rate of healing of the affected tissue, and the release of the degradation products should be within the body's acceptable absorption levels. Conventional magnesium degrades rapidly, which is undesirable. In this study, biodegradation behaviours of high purity magnesium and commercial purity magnesium alloy AZ31 in both static and dynamic Hank's solution have been systematically investigated. The results show that magnesium purification and selective alloying are effective approaches to reduce the degradation rate of magnesium. In the static condition, the corrosion products accumulate on the materials surface as a protective layer, which results in a lower degradation rate than the dynamic condition. Anodised coating can significantly further reduce the degradation rate of magnesium. This study indicates that magnesium can be used as degradable implant materials as long as the degradation is controlled at a low rate. Magnesium purification, selective alloying and anodised coating are three effective approaches to reduce the rate of degradation.