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Chemical composition and biological activities of Salvia officinalis essential oil from Tunisia

机译:突尼斯丹参药材的化学成分和生物活性

摘要

The aim of this study is to evaluate the chemical composition, antioxidant, antimicrobial, insecticidal and allelopa- thic activities of Tunisia Salvia officinalis essential oil (SoEO). The SoEO was characterized by the presence of 49 components with camphor (25.14 %), α-thujone (18.83 %), 1,8-cineole (14.14 %), viridiflorol (7.98 %), β-thu- jone (4.46 %) and β-caryophyllene (3.30 %) as the major components, determined by gas chromatography-mass spectrometry. The level of antioxidant activity, determined by complementary tests, namely 2,2-diphenyl-1-pic- rylhydrazyl radical-scavenging (IC50= 6.7 mg/mL), linoleic acid peroxidation (IC50= 9.6 mg/mL) and ferric reduc- ing assays (IC50= 28.4 mg/mL), was relatively moderate. The SoEO was also screened for its antimicrobial activity. Good to moderate inhibitions were recorded for most of tested microorganisms. It also exhibited important insec- ticidal activity against Spodoptera littoralis larvae and Tribolium castaneum adults with LC50 values of 55.99 and97.43 µl/L air, respectively. The effect of the SoEO on seeds germination and growth showed different activities against radical and hypocotyl elongation of the tested species. These results suggest the potential use of the SoEOas natural antimicrobial preservative in cosmetic, pharmaceutical industry and in pest management.
机译:这项研究的目的是评估突尼斯丹参药材(SoEO)的化学成分,抗氧化剂,抗菌剂,杀虫剂和化石活性。 SoEO的特征是存在49种成分,其中包括樟脑(25.14%),α-thujone(18.83%),1,8-cineole(14.14%),viridiflorol(7.98%),β-thu-jone(4.46%)气相色谱-质谱法测定以β-石竹烯为主要成分(3.30%)。抗氧化活性水平由补充测试确定,即清除2,2-二苯基-1-甲基-肼基自由基(IC50 = 6.7 mg / mL),亚油酸过氧化(IC50 = 9.6 mg / mL)和三价铁还原检测(IC50 = 28.4 mg / mL)相对中等。还对SoEO的抗微生物活性进行了筛选。记录了大多数测试微生物的良好至中度抑制作用。它还显示出对斜纹夜蛾幼虫和锥栗Tribolium castaneum成虫的重要杀虫活性,空气的LC50值分别为55.99和97.43 µl / L。 SoEO对种子发芽和生长的影响显示出不同的抗受试物种自由基和下胚轴伸长的活性。这些结果表明,SoEOas天然抗菌防腐剂在化妆品,制药工业和有害生物管理中的潜在用途。

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