Escherichia coli as a potential hydrocarbon conversion microorganism. Oxidation of aliphatic and aromatic compounds by recombinant E. coli in two-liquid phase (aqueous-organic) systems

摘要

The increased interest in the study of hydrocarbon utilizing microorganisms in recent years has been stimulated by the possibility of using their monooxygenases in the selective oxidation of aliphatic and aromatic compounds. As an example, long chain (C16) n-alkanes are converted to dicarboxylic acids by yeast. This type of bioconversion is useful because the regioselective and stereospecific introduction of oxygen into unactivated organic substrates by classical synthetic chemistry remains very difficult. Zie: General Conclusions