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Excemplify: A Flexible Template Based Solution, Parsing and Managing Data in Spreadsheets for Experimentalists

机译:示例:基于灵活模板的解决方案,为实验人员解析和管理电子表格中的数据

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摘要

In systems biology, quantitative experimental data is the basis of building mathematical models. In most of the cases, they are stored in Excel files and hosted locally. To have a public database for collecting, retrieving and citing experimental raw data as well as experimental conditions is important for both experimentalists and modelers. However, the great effort needed in the data handling procedure and in the data submission procedure becomes the crucial limitation for experimentalists to contribute to a database, thereby impeding the database to deliver its benefit. Moreover, manual copy and paste operations which are commonly used in those procedures increase the chance of making mistakes. Excemplify, a web-based application, proposes a flexible and adaptable template-based solution to solve these problems. Comparing to the normal template based uploading approach, which is supported by some public databases, rather than predefining a format that is potentiall impractical, Excemplify allows users to create their own experiment-specific content templates in different experiment stages and to build corresponding knowledge bases for parsing. Utilizing the embedded knowledge of used templates, Excemplify is able to parse experimental data from the initial setup stage and generate following stages spreadsheets automatically. The proposed solution standardizes the flows of data traveling according to the standard procedures of applying the experiment, cuts down the amount of manual effort and reduces the chance of mistakes caused by manual data handling. In addition, it maintains the context of meta-data from the initial preparation manuscript and improves the data consistency. It interoperates and complements RightField and SEEK as well.
机译:在系统生物学中,定量实验数据是建立数学模型的基础。在大多数情况下,它们存储在Excel文件中并在本地托管。建立一个公共数据库来收集,检索和引用实验原始数据以及实验条件对于实验者和建模者都是重要的。但是,在数据处理过程和数据提交过程中需要付出巨大的努力,这成为实验人员对数据库做出贡献的关键限制,从而阻碍了数据库的实现。此外,在那些过程中通常使用的手动复制和粘贴操作增加了犯错的机会。 Excemplify是一个基于Web的应用程序,提出了一种灵活且可调整的基于模板的解决方案来解决这些问题。与某些公共数据库支持的基于常规模板的上载方法相比,Excemplify无需预定义可能不可行的格式,而是允许用户在不同的实验阶段创建自己的特定于实验的内容模板,并为它们建立相应的知识库解析。利用所用模板的嵌入式知识,Excemplify能够解析初始设置阶段的实验数据并自动生成后续阶段的电子表格。提出的解决方案根据应用实验的标准程序来标准化数据传输的流程,从而减少了人工工作量,并减少了由人工数据处理引起的错误机会。此外,它从初始准备手稿维护元数据的上下文,并改善了数据的一致性。它可以互操作并补充RightField和SEEK。

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