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Performance analysis of a swept-source optical coherence tomography system with a quadrature interferometer and optical amplification

机译:具有正交干涉仪和光学放大的扫频光学相干层析成像系统的性能分析

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摘要

A performance analysis of signal to noise ratio for an optical coherence tomography system with quadrature detection and a semiconductor optical amplifier in the sample arm is discussed. The results are compared and discussed in relation to a conventional OCT system (without optical amplification). An increase of the signal to noise ratio up to 14 dB at a depth of 0.5 mmis obtained compared to the system without the optical amplifier. Overall, an improvement was demonstrated for signal coming from deeper regions within the samples. Arterial plaque from a myocardial infarction-prone Watanabe heritable hyperlipidemic (WHHLMI) rabbit is visualized and characterized using this system. Improvement of signal to noise ratio increases the penetration depth possible for OCT images, from 1 mm to 2 mm within the vessel wall of an artery. Preliminary results show that vulnerable plaque with fibrous cap, macrophage accumulations and calcification in the arterial tissue are measurable with this OCT system.
机译:讨论了在采样臂中具有正交检测和半导体光放大器的光学相干层析成像系统的信噪比性能分析。相对于常规OCT系统(不进行光学放大)对结果进行了比较和讨论。与没有光放大器的系统相比,在0.5毫米深度处的信噪比增加了14 dB。总体而言,从样品内部较深区域发出的信号得到了改善。使用该系统可视化并鉴定了心肌梗死易发性渡边遗传性高脂血症(WHHLMI)兔的动脉斑块。信噪比的提高可将OCT图像的穿透深度从动脉血管壁内的1 mm增加到2 mm。初步结果表明,使用该OCT系统可以测量到带有纤维帽,巨噬细胞积累和动脉钙化的脆弱斑块。

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