Synthesis of New Building Blocks: Toward the Analogs of Peptide Nucleic Acids (PNAs)

摘要

To obtain new analogs of peptide nucleic acids (PNAs), synthesis of the building block 14 has been achieved. Building block 14 has been derived from the coupling of the isothiocyanate derivative, 12 with 13. Isothiocyanate derivative 12 was obtained from S-aspartic acid derivative 5 in a number of steps.