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Projector Model for Efficient List-Mode Reconstruction in PET Scanners with Parallel Planar Detectors

机译:具有平行平面探测器的PET扫描仪中高效列表模式重构的投影仪模型

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摘要

We have developed a new projector model specifically tailored for fast list-mode tomographic reconstructions in Positron emission tomography (PET) scanners with parallel planar detectors. The model provides an accurate estimation of the probability distribution of coincidence events defined by pairs of scintillating crystals. This distribution is parameterized with 2D elliptical Gaussian functions defined in planes perpendicular to the main axis of the tube of response (TOR). The parameters of these Gaussian functions have been obtained by fitting Monte Carlo simulations that include positron range, acolinearity of gamma rays, as well as detector attenuation and scatter effects. The proposed model has been applied efficiently to list-mode reconstruction algorithms. Evaluation with Monte Carlo simulations over a rotating high resolution PET scanner indicates that this model allows to obtain better recovery to noise ratio in OSEM (ordered-subsets, expectation-maximization) reconstruction, if compared to list-mode reconstruction with symmetric circular Gaussian TOR model, and histogram-based OSEM with precalculated system matrix using Monte Carlo simulated models and symmetries.
机译:我们已经开发了一种新的投影仪模型,专门针对带有平行平面探测器的正电子发射断层扫描(PET)扫描仪中的快速列表模式断层扫描重建而设计。该模型提供了由闪烁晶体对定义的同时发生事件的概率分布的准确估计。使用在与响应管(TOR)的主轴垂直的平面中定义的2D椭圆高斯函数对此分布进行参数化。这些高斯函数的参数是通过拟合蒙特卡洛模拟获得的,其中包括正电子范围,伽马射线的共线性以及检测器的衰减和散射效应。所提出的模型已有效地应用于列表模式重建算法。与旋转对称高斯TOR模型的列表模式重建相比,通过旋转高分辨率PET扫描仪的蒙特卡洛模拟评估,表明该模型可以在OSEM(有序子集,期望最大化)重建中获得更好的恢复噪声比。 ,以及基于蒙特卡洛模拟模型和对称性的基于直方图的OSEM与预先计算的系统矩阵。

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