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Direct inhibition of PI3K in combination with dual HER2 inhibitors is required for optimal antitumor activity in HER2+ breast cancer cells

机译：与HER2双重抑制剂联合直接抑制PI3K是HER2 +乳腺癌细胞中最佳抗肿瘤活性所必需的

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Brent N Rexer; Siprachanh Chanthaphaychith; Kimberly Brown Dahlman; Carlos L Arteaga;
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1. Direct inhibition of PI3K in combination with dual HER2 inhibitors is required for optimal antitumor activity in HER2+ breast cancer cells [J] . Brent N Rexer, Siprachanh Chanthaphaychith, Kimberly Brown Dahlman, Breast Cancer Research . 2014,第1期

机译：与HER2双重抑制剂联合直接抑制PI3K是HER2 +乳腺癌细胞中最佳抗肿瘤活性所必需的
2. Combination of antibody that inhibits ligand-independent HER3 dimerization and a p110α inhibitor potently blocks pi3k signaling and growth of HER2+ breast cancers [J] . GarrettJ.T., SuttonC.R., KurupiR., Cancer research: The official organ of the American Association for Cancer Research, Inc . 2013,第19期

机译：抑制不依赖配体的HER3二聚化的抗体与p110α抑制剂的组合可有效阻断pi3k信号传导和HER2 +乳腺癌的生长
3. Inhibition of mammalian target of rapamycin is required for optimal antitumor effect of HER2 inhibitors against HER2-overexpressing cancer cells. [J] . Miller TW, Forbes JT, Shah Clinical cancer research: an official journal of the American Association for Cancer Research . 2009,第23期

机译：抑制哺乳动物雷帕霉素靶标是HER2抑制剂对过量表达HER2的癌细胞的最佳抗肿瘤作用所必需的。
4. Radiographic Detection of HER2+ Breast Cancer Cells Immunotargeted by Gold Nanoparticles [C] . Tracie L. McGinnity, Tyler E. Curtis, Tracy Vargo-Gogola, Society for Biomaterials annual meeting and exposition . 2019

机译：金纳米颗粒免疫靶向HER2 +乳腺癌细胞的放射学检测。
5. Role of Jagged1 in the Enrichment of Cancer Stem Cells in Her2+ Breast Cancer [D] . Shah, Deep S. 2017

机译：Jagged1在Her2 +乳腺癌中癌干细胞富集中的作用
6. Direct inhibition of PI3K in combination with dual HER2 inhibitors is required for optimal antitumor activity in HER2+ breast cancer cells [O] . Brent N Rexer, Siprachanh Chanthaphaychith, Kimberly Brown Dahlman, 2014

机译：与HER2双重抑制剂联合直接抑制PI3K是HER2 +乳腺癌细胞中最佳抗肿瘤活性所必需的
7. Grb2-SH3 ligand inhibits the growth of HER2+ cancer cells and has antitumor effects in human cancer xenografts alone and in combination with docetaxel. [O] . Gril Brunilde, Vidal Michel, Assayag Franck, 2007

机译：Grb2-SH3配体可抑制HER2 +癌细胞的生长，并在单独或与多西他赛联合使用时对人癌异种移植物具有抗肿瘤作用。

Direct inhibition of PI3K in combination with dual HER2 inhibitors is required for optimal antitumor activity in HER2+ breast cancer cells

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