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Metastatic EML4-ALK fusion detected by circulating DNA genotyping in an EGFR-mutated NSCLC patient and successful management by adding ALK inhibitors: a case report

机译：通过对EGFR突变的NSCLC患者进行循环DNA基因分型检测到转移性EML4-ALK融合，并通过添加ALK抑制剂成功治疗：病例报告

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Wenhua Liang; Qihua He; Ying Chen; Shaokun Chuai; Weiqiang Yin; Wei Wang; Guilin Peng; Caicun Zhou; Jianxing He;
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1. Upregulation of PD-L1 by EML4-ALK fusion protein mediates the immune escape in ALK positive NSCLC: Implication for optional anti-PD-1/PD-L1 immune therapy for ALK-TKIs sensitive and resistant NSCLC patients [J] . Hong Shaodong, Chen Nan, Fang Wenfeng, Oncoimmunology. . 2016,第3期

机译：EML4-ALK融合蛋白对PD-L1的上调介导ALK阳性NSCLC的免疫逃逸：对ALK-TKIs敏感和耐药NSCLC患者的可选抗PD-1 / PD-L1免疫疗法的意义
2. Managing the Isolated Central Nervous System Progression in Patients With Oncogene-Driven Metastatic NSCLC: Does Circulating Tumor DNA Add to Management? [J] . Li Tianhong Journal of thoracic oncology: official publication of the International Association for the Study of Lung Cancer . 2020,第3期

机译：在癌基因驱动的转移性NSCLC患者中管理孤立的中枢神经系统进展：循环肿瘤DNA是否加入管理？
3. Successful management of a lung cancer patient harbouring both EGFR mutation and EML4-ALK fusion gene with disseminated intravascular coagulation [J] . Kohei Fujita, Megumi Naka, Takanori Ito, Respiratory Medicine Case Reports . 2021,第a期

机译：成功管理肺癌患者患有 egfr 突变和 eml4-ahk 融合基因，弥漫性血管内凝固
4. Enumeration and ALK Investigation of Circulating Tumor Cells in Non-Small Cell Lung Cancer (NSCLC) Patients Using an Effective In Vivo Technology, the GILUPI CellCollector? [C] . Klaus Luecke, Lukasz Gasiorowski, Stefanie Herold, International Molecular Medicine Tri-Conference. . 2015

机译：使用有效的体内技术（Gilupi Cellcollector
5. Metastatic EML4-ALK fusion detected by circulating DNA genotyping in an EGFR-mutated NSCLC patient and successful management by adding ALK inhibitors: a case report [O] . Wenhua Liang, Qihua He, Ying Chen, 2016

机译：通过对EGFR突变的NSCLC患者进行循环DNA基因分型检测到转移性EML4-ALK融合并通过添加ALK抑制剂成功治疗：病例报告
6. A fully automated assay to detect the expression of pan-cytokeratins and of EML4-ALK fusion protein in circulating tumour cells (CTCs) predicts outcome of non-small cell lung cancer (NSCLC) patients [O] . Elisabetta Rossi, Michele Aieta, Alfredo Tartarone, 2021

机译：一种全自动测定以检测泛细胞角蛋白和EML4-ALK融合蛋白在循环肿瘤细胞（CTC）中的表达预测非小细胞肺癌（NSCLC）患者的结果

Metastatic EML4-ALK fusion detected by circulating DNA genotyping in an EGFR-mutated NSCLC patient and successful management by adding ALK inhibitors: a case report

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